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Pt 纳米颗粒耦合 WO 纳米片作为多酶模拟物用于比色检测和自由基清除。

Pt nanoparticle-coupled WO nanoplates as multi-enzyme mimetics for colorimetric detection and radical elimination.

机构信息

College of Science, Northeastern University, Shenyang, 110004, China.

出版信息

Anal Bioanal Chem. 2020 Jan;412(2):521-530. doi: 10.1007/s00216-019-02268-1. Epub 2019 Dec 13.

Abstract

Nanomaterials that exhibit enzyme-like activity (nanozymes) have attracted significant attention due to their potential for applications in analytical tests and in the biological field. In this study, an enzyme-like nanomaterial is developed by coupling Pt nanoparticles with WO (Pt/WO). The resultant nanocomposite nanomaterial exhibits peroxidase activity and catalase activity. Moreover, owing to the presence of W and W in WO, Pt/WO nanoplates demonstrate promise as scavengers of hydroxyl radicals. The Pt/WO composite nanoplates exhibit excellent peroxidase-like activity for the sensitive colorimetric detection of HO and blood glucose. These Pt/WO nanoplates are thought to be a promising tool for broad potential applications in biomedicine, biotechnology, and environmental chemistry. Pt nanoparticles anchored WO nanoplates (Pt/WO) as a multienzyme-like mimetics exhibits peroxidase activity and catalase activity. Furthermore, this composite can be acted scavengers of hydroxyl radicals.

摘要

由于在分析测试和生物领域的潜在应用,表现出酶样活性的纳米材料(纳米酶)引起了人们的极大关注。在这项研究中,通过将 Pt 纳米颗粒与 WO 耦合,制备了一种酶样纳米材料(Pt/WO)。所得的纳米复合材料表现出过氧化物酶和过氧化氢酶活性。此外,由于 WO 中存在 W 和 W,Pt/WO 纳米片有望成为羟基自由基的清除剂。Pt/WO 复合纳米片对 HO 和血糖的灵敏比色检测表现出优异的过氧化物酶样活性。这些 Pt/WO 纳米片有望成为在生物医学、生物技术和环境化学等广泛领域应用的有前途的工具。锚定在 WO 纳米片上的 Pt 纳米颗粒(Pt/WO)作为一种多酶样模拟物,表现出过氧化物酶和过氧化氢酶活性。此外,这种复合材料可以作为羟基自由基的清除剂。

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