College of Science, Northeastern University, Shenyang, 110004, China.
Anal Bioanal Chem. 2020 Jan;412(2):521-530. doi: 10.1007/s00216-019-02268-1. Epub 2019 Dec 13.
Nanomaterials that exhibit enzyme-like activity (nanozymes) have attracted significant attention due to their potential for applications in analytical tests and in the biological field. In this study, an enzyme-like nanomaterial is developed by coupling Pt nanoparticles with WO (Pt/WO). The resultant nanocomposite nanomaterial exhibits peroxidase activity and catalase activity. Moreover, owing to the presence of W and W in WO, Pt/WO nanoplates demonstrate promise as scavengers of hydroxyl radicals. The Pt/WO composite nanoplates exhibit excellent peroxidase-like activity for the sensitive colorimetric detection of HO and blood glucose. These Pt/WO nanoplates are thought to be a promising tool for broad potential applications in biomedicine, biotechnology, and environmental chemistry. Pt nanoparticles anchored WO nanoplates (Pt/WO) as a multienzyme-like mimetics exhibits peroxidase activity and catalase activity. Furthermore, this composite can be acted scavengers of hydroxyl radicals.
由于在分析测试和生物领域的潜在应用，表现出酶样活性的纳米材料（纳米酶）引起了人们的极大关注。在这项研究中，通过将 Pt 纳米颗粒与 WO 耦合，制备了一种酶样纳米材料（Pt/WO）。所得的纳米复合材料表现出过氧化物酶和过氧化氢酶活性。此外，由于 WO 中存在 W 和 W，Pt/WO 纳米片有望成为羟基自由基的清除剂。Pt/WO 复合纳米片对 HO 和血糖的灵敏比色检测表现出优异的过氧化物酶样活性。这些 Pt/WO 纳米片有望成为在生物医学、生物技术和环境化学等广泛领域应用的有前途的工具。锚定在 WO 纳米片上的 Pt 纳米颗粒（Pt/WO）作为一种多酶样模拟物，表现出过氧化物酶和过氧化氢酶活性。此外，这种复合材料可以作为羟基自由基的清除剂。
