经颅近红外刺激可能会增加在人类中记录到的皮质兴奋性。
Transcranial near-infrared stimulation may increase cortical excitability recorded in humans.
机构信息
Central Laboratory, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, 100053, Beijing, China; Beijing Geriatric Medical Research Center, 45 Changchun Street, 100053, Beijing, China; Department of Neurology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, 100053, Beijing, China.
Department of Neurology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, 100053, Beijing, China.
出版信息
Brain Res Bull. 2020 Feb;155:155-158. doi: 10.1016/j.brainresbull.2019.12.007. Epub 2019 Dec 16.
OBJECTIVE
Transcranial near-infrared stimulation (tNIRS) can penetrate the scalp and skull and can reach the superficial layers of the cerebral cortex. In this study, we evaluated whether an 820-nm tNIRS can modulate the excitability of the primary motor cortex (M1) as measured by transcranial magnetic stimulation (TMS).
METHODS
tNIRS was applied at a wavelength of 820-nm for 4 min over the representation of the right first dorsal interosseous muscle (FDI) in the left M1, in 12 healthy right-handed participants. Motor evoked potentials (MEPs) from the FDI elicited by single-pulse TMS were measured at baseline and up to 30 min after the tNIRS.
RESULTS
The ΔMEPs percentage was evaluated, and a significant increase in amplitude was observed 10-20 min post-stimulation compared to that in sham.
CONCLUSION
This study provides evidence that an 820-nm tNIRS induces transitory increase in the excitability of the stimulated cortex.
目的
经颅近红外刺激（tNIRS）可穿透头皮和颅骨，到达大脑皮层的浅层。本研究旨在评估 820nm 的 tNIRS 是否可以通过经颅磁刺激（TMS）来调节初级运动皮层（M1）的兴奋性。
方法
在 12 名健康的右利手参与者中，在左侧 M1 中代表右手第一背侧骨间肌（FDI）的位置，用 820nm 的波长进行 4 分钟的 tNIRS。在基线和 tNIRS 后 30 分钟内，通过单次 TMS 测量 FDI 诱发的运动诱发电位（MEP）。
结果
评估了 ΔMEPs 的百分比，与假刺激相比，刺激后 10-20 分钟观察到振幅显著增加。
结论
本研究提供的证据表明，820nm 的 tNIRS 可引起刺激皮层的兴奋性短暂增加。
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