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不同动物物种中L-丝氨酸脱水酶和L-丝氨酸-丙酮酸转氨酶的活性。

L-serine dehydratase and L-serine-pyruvate aminotransferase activities in different animal species.

作者信息

Rowsell E V, Carnie J A, Wahbi S D, Al-Tai A H, Rowsell K V

机构信息

Department of Biochemistry, University of Manchester, Institute of Science and Technology, England.

出版信息

Comp Biochem Physiol B. 1979;63(4):543-55. doi: 10.1016/0305-0491(79)90061-0.

DOI:10.1016/0305-0491(79)90061-0
PMID:318433
Abstract
  1. A rough inverse correlation between liver serine dehydratase activity and species body size was observed with mammals. This was not found for glutamate, malate or lactate dehydrogenase, fumarase or aspartate-2-oxoglutarate aminotransferase. Serine dehydratase (and certain liver aminotransferases showing a similar species-size dependence) may have a role in the stimulation of heat production. 2. Cold-exposed rats showed a 3-4 fold increase in serine dehydratase activity. 3. No liver serine dehydratase was measurable in amphibia. 4. In mammals high liver serine-pyruvate aminotransferase is associated with a flesh-eating dietary habit. High activity was found in amphibia and goldfish. A gluconeogenic role is suggested.
摘要
  1. 在哺乳动物中观察到肝脏丝氨酸脱水酶活性与物种体型之间存在大致的负相关。而谷氨酸、苹果酸或乳酸脱氢酶、延胡索酸酶或天冬氨酸 - 2 - 酮戊二酸氨基转移酶则未发现这种情况。丝氨酸脱水酶(以及某些显示出类似物种大小依赖性的肝脏氨基转移酶)可能在刺激产热中发挥作用。2. 冷暴露的大鼠丝氨酸脱水酶活性增加了3 - 4倍。3. 在两栖动物中未检测到肝脏丝氨酸脱水酶。4. 在哺乳动物中,高肝脏丝氨酸 - 丙酮酸氨基转移酶与肉食性饮食习惯相关。在两栖动物和金鱼中发现了高活性。提示其具有糖异生作用。

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1
L-serine dehydratase and L-serine-pyruvate aminotransferase activities in different animal species.不同动物物种中L-丝氨酸脱水酶和L-丝氨酸-丙酮酸转氨酶的活性。
Comp Biochem Physiol B. 1979;63(4):543-55. doi: 10.1016/0305-0491(79)90061-0.
2
Regulation of hepatic L-serine dehydratase and L-serine-pyruvate aminotransferase in the developing neonatal rat.新生大鼠发育过程中肝脏L-丝氨酸脱水酶和L-丝氨酸-丙酮酸转氨酶的调节
Biochem J. 1974 Dec;144(3):519-31. doi: 10.1042/bj1440519.
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Increased liver L-serine-pyruvate aminotransferase activity under gluconeogenic conditions.在糖异生条件下肝脏L-丝氨酸-丙酮酸转氨酶活性增加。
Biochem J. 1973 May;134(1):349-51. doi: 10.1042/bj1340349.
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Immunochemical studies of serine dehydratase and ornithine aminotransferase regulation in rat liver in vivo.大鼠肝脏中丝氨酸脱水酶和鸟氨酸氨基转移酶体内调节的免疫化学研究。
J Biol Chem. 1976 May 10;251(9):2571-8.
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Enzymes of serine metabolism in normal, developing and neoplastic rat tissues.正常、发育中和肿瘤大鼠组织中丝氨酸代谢的酶
Adv Enzyme Regul. 1984;22:325-400. doi: 10.1016/0065-2571(84)90021-9.
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[The key enzymes of the alternative pathways of serine utilization in gluconeogenesis in chickens during individual development].[鸡个体发育过程中糖异生作用中丝氨酸利用替代途径的关键酶]
Zh Evol Biokhim Fiziol. 1990 May-Jun;26(3):424-6.
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Hormonal and dietary control of enzymes in the rat. 3. The regulation of liver serine dehydratase and ornithine delta-aminotransferase in hypophysectomized-pancreatectomized rats.大鼠体内酶的激素与饮食调控。3. 垂体切除-胰腺切除大鼠肝脏丝氨酸脱水酶和鸟氨酸δ-氨基转移酶的调节
J Biochem. 1971 May;69(5):829-37. doi: 10.1093/oxfordjournals.jbchem.a129534.
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Dietary effects on rat liver enzymes in meal-fed rats.日粮对定时喂食大鼠肝脏酶的影响。
J Nutr. 1968 Nov;96(3):382-90. doi: 10.1093/jn/96.3.382.
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Gluconeogenesis from serine by the serine-dehydratase-dependent pathway in rat liver.大鼠肝脏中通过丝氨酸脱水酶依赖性途径由丝氨酸进行的糖异生作用。
Eur J Biochem. 1974 Apr 16;43(3):609-16. doi: 10.1111/j.1432-1033.1974.tb03448.x.
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[Difference in the activity of enzymes of glucolytic amino acids in the rat liver].
Klin Wochenschr. 1971 Sep 1;49(17):992-3. doi: 10.1007/BF01489466.

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