在糖异生条件下肝脏L-丝氨酸-丙酮酸转氨酶活性增加。
Increased liver L-serine-pyruvate aminotransferase activity under gluconeogenic conditions.
作者信息
Rowsell E V, al-Tai A H, Carnie J A
出版信息
Biochem J. 1973 May;134(1):349-51. doi: 10.1042/bj1340349.
Abstract
Rat liver l-serine-pyruvate aminotransferase activity exceeds markedly the normal adult value (a) in the neonatal period, (b) after glucagon injection and (c) after alloxan injection, observations that reinforce the suggestion from comparative findings that the aminotransferase has a role in gluconeogenesis. Some findings, however, argue in favour of l-serine dehydratase as the enzyme of gluconeogenesis from l-serine.
摘要
大鼠肝脏L-丝氨酸-丙酮酸转氨酶活性在以下情况下显著超过正常成年值：(a) 新生儿期；(b) 注射胰高血糖素后；(c) 注射四氧嘧啶后。这些观察结果进一步支持了比较研究结果所提出的观点，即该转氨酶在糖异生过程中起作用。然而，一些研究结果支持L-丝氨酸脱水酶是L-丝氨酸糖异生的酶。
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CARBOHYDRATE METABOLISM IN LIVER FROM FOETAL AND NEONATAL SHEEP.胎儿和新生绵羊肝脏中的碳水化合物代谢
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