Liu Zhen-Zhen, Long Er-Ping, Lin Duo-Ru, Ye Lei, Xiang Yi-Fan, Li Wang-Ting, Wu Xiao-Hang, Zhao Xu-Tu, Liu Xiao-Ping, Zhao Lan-Qin, Huang Xiu-Cheng, Yu Tong-Yong, Chen Hui, Chen Jing-Jing, Wu Ming-Xing, Lin Hao-Tian, Chen Wei-Rong, Liu Yi-Zhi
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510000, Guangdong Province, China.
Int J Ophthalmol. 2019 Dec 18;12(12):1839-1847. doi: 10.18240/ijo.2019.12.04. eCollection 2019.
To study the change in ocular refraction in patients with pediatric cataracts (PCs) after lens extraction.
A total of 1258 patients who were undergoing cataract extraction with/without intraocular lens (IOL) implantation were recruited during preoperative examinations between Jan 2010 and Oct 2013. Patient ages ranged from 1.5mo to 14y. Follow-ups were conducted at 1wk, 1, and 3mo postoperatively and every 3mo in the first year, then 6mo thereafter. Ocular refraction [evaluated as spherical equivalent (SE)] and yearly myopic shift (YMS) were recorded and statistically analyzed among patients with age at surgery, baseline ocular refraction, gender, postoperative time and laterality (bilateral unilateral).
By Dec 31 2015, 1172 participants had been followed for more than 2y. The median follow-up period was 3y. The critical factors affecting the ocular refraction of PC patients were baseline ocular refraction, postoperative time for both aphakic and pseudophakic eyes. YMS grew most rapidly in young childhood and early adolescence.
After lens surgeries, ocular refraction in PC patients shows an individual difference of change. Further concerns should be raising to monitor the rapid myopic shift at early adolescence of these patients.
研究儿童白内障（PC）患者晶状体摘除术后眼屈光的变化。
2010年1月至2013年10月术前检查期间，共招募了1258例行白内障摘除术（伴或不伴人工晶状体植入）的患者。患者年龄从1.5个月至14岁。术后1周、1个月和3个月进行随访，术后第一年每3个月随访一次，此后每6个月随访一次。记录手术年龄、基线眼屈光、性别、术后时间和侧别（双侧/单侧）患者的眼屈光[以等效球镜度（SE）评估]和每年近视度数变化（YMS），并进行统计学分析。
截至2015年12月31日，1172名参与者随访时间超过2年。中位随访期为3年。影响PC患者眼屈光的关键因素是无晶状体眼和人工晶状体眼的基线眼屈光和术后时间。YMS在幼儿期和青春期早期增长最快。
晶状体手术后，PC患者的眼屈光变化存在个体差异。应进一步关注监测这些患者青春期早期的快速近视度数变化。
