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周围组织对表面处理氧化锆种植体的反应。

Surrounding Tissue Response to Surface-Treated Zirconia Implants.

作者信息

Iinuma Yohei, Hirota Masatsugu, Hayakawa Tohru, Ohkubo Chikahiro

机构信息

Department of Removable Prosthodontics, School of Dental Medicine, Tsurumi University, 2-1-3, Tsurumi, Yokohama, Kanagawa 230-8501, Japan.

School of Dental Medicine, Tsurumi University, 2-1-3, Tsurumi, Yokohama, Kanagawa 230-8501, Japan.

出版信息

Materials (Basel). 2019 Dec 19;13(1):30. doi: 10.3390/ma13010030.

DOI:10.3390/ma13010030
PMID:31861679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6981750/
Abstract

Yttria-stabilized tetragonal zirconia polycrystals (Y-TZP), which are partially stabilized zirconia, have been used for fabricating dental implants. This study investigated the soft tissue attachment, the collagen fiber orientation to zirconia at different surface conditions, and the bone response using implantation experiments in animals. The zirconia implant surfaces were treated with ultraviolet irradiation (UV), a combination of large-grit sandblasting and hydrofluoric acid etching (blastedHF), and a combination of blastedHF and UV (blastedHF+UV). The surface treated with blastedHF and blastedHF+UV appeared rough and hydrophilic. The surface treated with blastedHF+UV appeared to be superhydrophilic. Subsequently, tapered cylindrical zirconia implants were placed in the alveolar sockets of the maxillary molars of rats. The bone-to-implant contact ratio of blastedHF and blastedHF+UV implants was significantly higher than that of the non-treated controls and UV-treated implants. The four different surface-treated zirconia implants demonstrated tight soft tissue attachments. Perpendicularly oriented collagen fibers towards zirconia implants were more prominent in blastedHF and blastedHF+UV implants compared to the controls and UV-treated implants. The area of the soft tissue attachment was the greatest with the perpendicularly oriented collagen fibers of blastedHF+UV-treated implants. In conclusion, blastedHF+UV treatment could be beneficial for ensuring greater soft-tissue attachment for zirconia implants.

摘要

钇稳定四方氧化锆多晶体（Y-TZP）是部分稳定的氧化锆，已被用于制造牙科植入物。本研究通过动物植入实验，研究了不同表面条件下软组织附着情况、胶原纤维对氧化锆的取向以及骨反应。氧化锆植入物表面分别用紫外线照射（UV）、粗粒度喷砂和氢氟酸蚀刻组合处理（喷砂HF）以及喷砂HF和UV组合处理（喷砂HF+UV）。经喷砂HF和喷砂HF+UV处理的表面显得粗糙且亲水。经喷砂HF+UV处理的表面似乎具有超亲水性。随后，将锥形圆柱形氧化锆植入物植入大鼠上颌磨牙的牙槽窝中。喷砂HF和喷砂HF+UV植入物的骨与植入物接触率显著高于未处理的对照和UV处理的植入物。四种不同表面处理的氧化锆植入物均表现出紧密的软组织附着。与对照和UV处理的植入物相比，喷砂HF和喷砂HF+UV植入物中朝向氧化锆植入物垂直排列的胶原纤维更为突出。喷砂HF+UV处理植入物垂直排列的胶原纤维的软组织附着面积最大。总之，喷砂HF+UV处理可能有利于确保氧化锆植入物获得更大的软组织附着。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/74eb3e744d09/materials-13-00030-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/2ca763a3ca97/materials-13-00030-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/1d62fea49c24/materials-13-00030-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/6e04cc8ec9e6/materials-13-00030-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/25851e6a881d/materials-13-00030-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/74eb3e744d09/materials-13-00030-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/2ca763a3ca97/materials-13-00030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/02d799e88c90/materials-13-00030-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/6fa4558efe8a/materials-13-00030-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/4ac6ccb66741/materials-13-00030-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/1cf7510c9b94/materials-13-00030-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/1d62fea49c24/materials-13-00030-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/6e04cc8ec9e6/materials-13-00030-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/25851e6a881d/materials-13-00030-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea8/6981750/74eb3e744d09/materials-13-00030-g009.jpg

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