Oral Health Science Center, Tokyo Dental College.
Dent Mater J. 2020 Jan 31;39(1):37-45. doi: 10.4012/dmj.2019-151. Epub 2019 Oct 30.
Zirconia have been applied to dental implants as well as fixed dental prostheses due to their mechanical, esthetic and biocompatible performance. Moreover, they offer an advantage over titanium (Ti) implants, in that there is no risk of discoloration or hypersensitive reaction with allergy. In this review, the durability and tissue-compatibility of zirconia for the oral implants was mainly discussed. Hot isostatic pressing of Y-TZP had higher cyclic fatigue strength than Cp-Ti (Grade-2), leading the sufficient durability. Tissue-compatibility of zirconia; 1) Blast and acid-etching was effective for bone formation with synergetic effect of micro- and nano-topography. 2) Super-hydrophilic treatment, cold plasma in particular, enhanced initial attachment of osteoblast-like cells and oral keratinocytes. 3) Adherence of the periodontopathic bacteria on zirconia was similar to that on Cp-Ti, leading the necessity of surface modification.
氧化锆因其机械、美观和生物相容性性能而被应用于牙科种植体和固定义齿。此外，与钛（Ti）种植体相比，氧化锆还有一个优势，即不会有变色或过敏反应的风险。在这篇综述中，主要讨论了氧化锆用于口腔种植体的耐用性和组织相容性。热等静压 Y-TZP 的循环疲劳强度高于 Cp-Ti（Grade-2），具有足够的耐用性。氧化锆的组织相容性；1）喷砂酸蚀对于骨形成是有效的，具有微观和纳米形貌的协同作用。2）超亲水处理，特别是冷等离子体，增强了成骨样细胞和口腔角质形成细胞的初始附着。3）牙周病细菌在氧化锆上的黏附与在 Cp-Ti 上相似，因此需要进行表面改性。
