Department of Kinesiology, Michigan State University, East Lansing, Michigan, USA.
Department of Kinesiology, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Sci Rep. 2019 Dec 20;9(1):19583. doi: 10.1038/s41598-019-55925-x.
Little is known about whether physical activity and fitness could enhance cognition in adolescents and young adults living with HIV. The purpose of this study was to examine this relationship in a group of 250 HIV+ (n = 88) and HIV negative (n = 162) participants from Botswana, aged 12-23 years (Mean = 17.87, SD = 2.24). Fitness was operationalized as muscular strength (push-ups) and aerobic endurance (PACER). PA was assessed using items from the Youth Risk Behavior Surveillance Survey. Cognition was measured using the Corsi Test, Berg Card Sorting Task (BCST), and Stroop Color Word Task (Stroop). Multiple regression analyses indicated that the HIV x push-ups interaction was a significant predictor of Corsi performance, and HIV status was a significant predictor of BCST performance (p < 0.05). For the Stroop portions, HIV status and HIV x push-ups were significant predictors (p < 0.01). HIV status is predictive of cognition and interacts with muscular fitness to predict cognition.
目前对于身体活动和健康是否可以增强 HIV 感染者青少年和年轻成年人的认知能力知之甚少。本研究的目的是在来自博茨瓦纳的 250 名 HIV 阳性（n=88）和 HIV 阴性（n=162）参与者中检查这种关系，他们的年龄在 12-23 岁之间（平均=17.87，标准差=2.24）。体能被定义为肌肉力量（俯卧撑）和有氧耐力（PACER）。PA 使用来自 Youth Risk Behavior Surveillance Survey 的项目进行评估。认知能力使用 Corsi 测试、Berg 卡片分类任务（BCST）和 Stroop 颜色词任务（Stroop）进行测量。多元回归分析表明，HIV x 俯卧撑的相互作用是 Corsi 表现的显著预测因素，而 HIV 状态是 BCST 表现的显著预测因素（p<0.05）。对于 Stroop 部分，HIV 状态和 HIV x 俯卧撑是显著的预测因素（p<0.01）。HIV 状态是认知能力的预测因素，并且与肌肉健康相互作用以预测认知能力。
