Hospices Civils de Lyon, Louis Pradel Cardiology Hospital, Lyon, France.
Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, Lyon, France.
Sci Rep. 2019 Dec 27;9(1):19850. doi: 10.1038/s41598-019-56427-6.
Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a new prototype spectral photon-counting CT (SPCCT) based on a modified clinical CT system has been tested in a feasibility study for improving vascular lumen delineation and visualization of coronary stent architecture. Coronary stents of different metal composition were deployed inside plastic tubes containing hydroxyapatite spheres to simulate vascular calcifications and in the abdominal aorta of one New Zealand White (NZW) rabbit. Imaging was performed with an SPCCT prototype, a dual-energy CT system, and a conventional 64-channel CT system (B64). We found the apparent widths of the stents significantly smaller on SPCCT than on the other two systems in vitro (p < 0.01), thus closer to the true size. Consequently, the intra-stent lumen was significantly larger on SPCCT (p < 0.01). In conclusion, owing to the increased spatial resolution of SPCCT, improved lumen visualization and delineation of stent metallic mesh is possible compared to dual-energy and conventional CT.
由于金属支架和血管钙化引起的blooming 伪影,标准计算机断层扫描(CT)中血管管腔的可视化受到影响。最近,由于在 X 射线成像领域引入了光子计数探测器,一种基于改良临床 CT 系统的新型光子计数光谱 CT(SPCCT)原型已在一项改善血管管腔描绘和冠状动脉支架结构可视化的可行性研究中进行了测试。在含有羟基磷灰石球体的塑料管内植入不同金属成分的冠状动脉支架,以模拟血管钙化,并植入一只新西兰白兔的腹主动脉内。使用 SPCCT 原型、双能 CT 系统和常规 64 通道 CT 系统(B64)进行成像。我们发现,支架在体外的 SPCCT 上的表观宽度明显小于其他两种系统(p < 0.01),因此更接近真实尺寸。因此,支架内管腔在 SPCCT 上明显更大(p < 0.01)。总之,由于 SPCCT 的空间分辨率提高,与双能 CT 和常规 CT 相比,SPCCT 可实现更好的管腔可视化和支架金属网的描绘。