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一项关于用双乙烯亚胺灭活的新城疫病毒的初步疫苗效力试验。

A preliminary vaccine potency trial of a Newcastle disease virus inactivated with binary ethylenimine.

作者信息

Buonavoglia C, Fioretti A, Tollis M, Menna F, Papparella V

机构信息

Istituto Superiore di Sanità, Laboratorio di Medicina Veterinaria, Roma, Italy.

出版信息

Vet Res Commun. 1988;12(2-3):195-7. doi: 10.1007/BF00362801.

DOI:10.1007/BF00362801
PMID:3188387
Abstract

Inactivation of Newcastle Disease Virus (NDV) by binary ethylenimine (BEI) is reported. The activity of an oil vaccine prepared with BEI-inactivated NDV was compared to a vaccine prepared with formalin-inactivated NDV. The BEI inactivated vaccine had almost twice the efficacy.

摘要

据报道，二乙烯亚胺（BEI）可使新城疫病毒（NDV）失活。将用BEI灭活的NDV制备的油乳剂疫苗的活性与用福尔马林灭活的NDV制备的疫苗进行了比较。BEI灭活疫苗的效力几乎是后者的两倍。

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本文引用的文献

1
Rabies virus inactivation by binary ethylenimine: new method for inactivated vaccine production.用双乙撑亚胺灭活狂犬病病毒：生产灭活疫苗的新方法。
J Clin Microbiol. 1980 Feb;11(2):120-2. doi: 10.1128/jcm.11.2.120-122.1980.
2
An inactivated, oil-emulsion vaccine for the prevention of porcine parvovirus-induced reproductive failure.一种用于预防猪细小病毒引起的繁殖障碍的灭活油乳剂疫苗。
Res Vet Sci. 1984 Mar;36(2):136-43.
3
Comparison of pseudorabies virus inactivated by bromo-ethylene-imine, 60Co irradiation, and acridine dye in immune assay systems.
用双乙烯亚胺和福尔马林使传染性法氏囊病病毒失活。
J Zhejiang Univ Sci B. 2006 Apr;7(4):320-3. doi: 10.1631/jzus.2006.B0320.
4
Sucrose density gradient centrifugation and cross-flow filtration methods for the production of arbovirus antigens inactivated by binary ethylenimine.用于生产经双乙烯亚胺灭活的虫媒病毒抗原的蔗糖密度梯度离心法和错流过滤法
BMC Microbiol. 2004 Jan 14;4:3. doi: 10.1186/1471-2180-4-3.
5
Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine.用于疫苗制备的病毒抗原灭活，特别提及双乙烯亚胺的应用
Vaccine. 1990 Aug;8(4):299-303. doi: 10.1016/0264-410x(90)90083-x.
J Clin Microbiol. 1978 Nov;8(5):604-11. doi: 10.1128/jcm.8.5.604-611.1978.
4
Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production.二乙烯亚胺作为口蹄疫病毒的灭活剂及其在疫苗生产中的应用。
Arch Virol. 1975;47(1):47-56. doi: 10.1007/BF01315592.