Living Systems Institute, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Philos Trans R Soc Lond B Biol Sci. 2020 Feb 17;375(1792):20190148. doi: 10.1098/rstb.2019.0148. Epub 2019 Dec 30.
Cilia are specialized cellular organelles that are united in structure and implicated in diverse key life processes across eukaryotes. In both unicellular and multicellular organisms, variations on the same ancestral form mediate sensing, locomotion and the production of physiological flows. As we usher in a new, more interdisciplinary era, the way we study cilia is changing. This special theme issue brings together biologists, biophysicists and mathematicians to highlight the remarkable range of systems in which motile cilia fulfil vital functions, and to inspire and define novel strategies for future research. This article is part of the Theo Murphy meeting issue 'Unity and diversity of cilia in locomotion and transport'.
纤毛是结构上相统一的特化细胞器官,在真核生物的多种关键生命过程中都发挥作用。在单细胞生物和多细胞生物中,同一祖先形式的变体介导感觉、运动和生理流动的产生。随着我们进入一个新的、更加跨学科的时代,我们研究纤毛的方式正在发生变化。本期特刊汇集了生物学家、生物物理学家和数学家,重点介绍了运动纤毛发挥重要功能的各种系统,并为未来的研究激发和定义了新的策略。本文是 Theo Murphy 会议特刊“纤毛在运动和运输中的统一与多样性”的一部分。