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手部小关节化脓性关节炎的Masquelet技术:病例报告。

The Masquelet technique for septic arthritis of the small joint in the hands: Case reports.

作者信息

Saito Taichi, Noda Tomoyuki, Kondo Hiroya, Demiya Koji, Nezu Satoshi, Yokoo Suguru, Matsuhashi Minami, Uehara Takenori, Shimamura Yasunori, Kodama Masayuki, Ozaki Toshifumi

机构信息

Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Density and Pharmaceutical Sciences, Okayama, Japan.

Department of Musculoskeletal Traumatology, Okayama University Graduate School of Medicine, Density and Pharmaceutical Sciences, Okayama, Japan.

出版信息

Trauma Case Rep. 2019 Dec 17;25:100268. doi: 10.1016/j.tcr.2019.100268. eCollection 2020 Feb.

Abstract

Septic arthritis in distal interphalangeal (DIP) joints sometimes occurs in association with mucous cysts or after the surgical treatment of mallet fingers. Recently, several studies have demonstrated the effectiveness of the Masquelet technique in the treatment of bone defects caused by trauma or infection. However, only few studies have reported the use of this technique for septic arthritis in small joints of the hand, and its effectiveness in treating septic arthritis in DIP joints remains unclear. We report the clinical and radiological outcomes of three patients who were treated with the Masquelet technique for septic arthritis in DIP joints. One patient had uncontrolled diabetes and another had rheumatoid arthritis treated with methotrexate and prednisolone. The first surgical stage involved thorough debridement of the infection site, including the middle and distal phalanx. We placed an external fixator from the middle to the distal phalanx and then packed the cavity of the DIP joint with antibiotic cement bead of polymethylmethacrylate (40 g) including 2 g of vancomycin and 200 mg of minocycline. At 4-6 weeks after the first surgical stage, the infection had cleared, and the second surgical stage was performed. The external fixator and cement bead were carefully removed while carefully preserving the surrounding osteo-induced membrane. The membrane was smooth and nonadherent to the cement block. In the second surgical stage, an autogenous bone graft was harvested from the iliac bone and inserted into the joint space, within the membrane. The bone graft, distal phalanx, and middle phalanx were fixed with Kirschner wires and/or a soft wire. Despite the high risk of infection, bone union was achieved in all patients without recurrence of infection. Although the Masquelet technique requires two surgeries, it can lead to favorable clinical and radiological outcomes for infected small joints of the hand.

摘要

远侧指间关节(DIP)的化脓性关节炎有时与黏液囊肿相关,或在锤状指手术治疗后发生。最近,多项研究已证明Masquelet技术在治疗由创伤或感染引起的骨缺损方面的有效性。然而,仅有少数研究报道了该技术在手部小关节化脓性关节炎治疗中的应用,其治疗DIP关节化脓性关节炎的有效性仍不明确。我们报告了3例采用Masquelet技术治疗DIP关节化脓性关节炎患者的临床和影像学结果。1例患者患有未得到控制的糖尿病,另1例患有类风湿关节炎,正在接受甲氨蝶呤和泼尼松龙治疗。首次手术阶段包括对感染部位进行彻底清创,包括中节和远节指骨。我们从指骨中部至远部放置了外固定架,然后用含2 g万古霉素和200 mg米诺环素的聚甲基丙烯酸甲酯抗生素骨水泥珠(40 g)填充DIP关节腔。在首次手术阶段后的4至6周,感染已清除,遂进行了第二次手术阶段。小心移除外固定架和骨水泥珠,同时小心保留周围的骨诱导膜。该膜光滑,不粘连于骨水泥块。在第二次手术阶段,从髂骨获取自体骨移植并植入膜内的关节间隙。用克氏针和/或软钢丝固定骨移植块、远节指骨和中节指骨。尽管感染风险高,但所有患者均实现了骨愈合,且无感染复发。虽然Masquelet技术需要进行两次手术,但它可为手部感染的小关节带来良好的临床和影像学结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b93c/6926348/8efb1c3d6a30/gr1.jpg

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