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老年人肺炎预防:另一面。

Pneumonia prevention in the elderly patients: the other sides.

机构信息

Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.

Division of Internal Medicine of the Aged, Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals, University of Geneva, Geneva, Switzerland.

出版信息

Aging Clin Exp Res. 2021 Apr;33(4):1091-1100. doi: 10.1007/s40520-019-01437-7. Epub 2019 Dec 31.

Abstract

Pneumonia is one of the leading causes of morbidity and mortality from infection in elderly patients. The increased frequency of pneumonia among elderly subjects can be explained by the physiological changes linked to the progressive aging of the respiratory tree and the diminished immunological response. A spiral of event leads to frailty, infection and possible death; preventing pneumonia consists of controlling the risk factors. Dysphagia, which is associated with malnutrition and dehydration, is recognized as one of the major pathophysiological mechanism leading to pneumonia and its screening is crucial for the pneumonia risk assessment. The impairment in the oropharyngeal reflexes results in stagnation of foreign material in the lateral cavities of the pharynx which may then get aspirated repeatedly in the lungs and cause pneumonia. Pneumonia prevention starts with lifestyle modifications such as alcohol and tobacco cessation. A careful review of the risk-benefit of the prescribed medication is critical and adaptation may be required in elders with multiple morbidities. Respiratory physiotherapy and mobilization improve the functional status and hence may help reduce the risk of pneumonia. Maintaining teeth and masticatory efficiency is important if malnutrition and its consequences are to be avoided. Daily oral hygiene and regular professional removal of oral biofilm can prevent the onset of periodontitis and can avoid an oral environment favoring the colonization of respiratory pathogens than can then be aspirated into the lungs.

摘要

肺炎是导致老年患者感染发病率和死亡率的主要原因之一。老年人肺炎发病率增加的原因可以用与呼吸道树渐进性老化和免疫反应减弱相关的生理变化来解释。一系列的事件导致虚弱、感染和可能的死亡;预防肺炎包括控制危险因素。与营养不良和脱水有关的吞咽困难被认为是导致肺炎的主要病理生理机制之一,对其进行筛查对于肺炎风险评估至关重要。口咽反射的损伤导致异物在咽的侧腔中停滞,这些异物可能会反复被吸入肺部,导致肺炎。肺炎的预防始于生活方式的改变,如戒烟和戒酒。仔细审查处方药物的风险-获益比至关重要,对于患有多种疾病的老年人可能需要进行调整。呼吸理疗和运动可以改善功能状态,从而有助于降低肺炎的风险。保持牙齿和咀嚼效率很重要,以避免营养不良及其后果。每日口腔卫生和定期专业清除口腔生物膜可以预防牙周炎的发生,并避免有利于呼吸道病原体定植的口腔环境,这些病原体随后可能被吸入肺部。

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