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吲哚菁绿荧光引导下合并门静脉癌栓的肝癌解剖性肝段切除术:反荧光技术。

Indocyanine-green fluorescence guided anatomical segmentectomy for HCC with portal thrombosis: the counter-fluorescence technique.

机构信息

Division of Hepatobiliary and General Surgery, Department of Surgery, Humanitas Research Hospital-IRCCS, Humanitas University, Via A. Manzoni, 56, 20089, Rozzano, MI, Italy.

出版信息

Updates Surg. 2020 Mar;72(1):219-222. doi: 10.1007/s13304-019-00695-4. Epub 2020 Jan 1.

Abstract

A surgical technique to intra-operatively define segmental boundaries by US-guided bimanual liver compression has been described by the authors, but this procedure is contraindicated in case of portal tumor thrombus. A technique to overcome this limitation is described. A patient with a single hepatocarcinoma nodule and segment 8 (S8) portal branch thrombosis was submitted to the procedure. Anatomical demarcation of S8 was achieved by hilar clamping of the common hepatic artery, intravenous injection of indocyanine green (ICG), and fluorescence imaging analyses of the liver. The procedure was feasible and the demarcation of S8 was visible within 2 min from the iv injection of ICG in a counterstaining fashion. Then S8 segmentectomy was safely carried out. This novel approach seems feasible, providing a reliably anatomical and conservative removal of HCC with portal branch tumor thrombus.

摘要

作者描述了一种通过超声引导双手肝压迫术术中定义节段边界的手术技术,但该技术在门静脉肿瘤血栓的情况下是禁忌的。本文介绍了一种克服这一限制的技术。一名患有单个肝癌结节和 8 段(S8)门静脉分支血栓的患者接受了该手术。通过肝总动脉的肝门夹闭、吲哚菁绿(ICG)的静脉注射以及肝脏荧光成像分析来实现 S8 的解剖边界划分。该手术可行,从 ICG 静脉注射后 2 分钟内即可通过对比染色的方式清晰显示 S8 的边界。然后安全地进行了 S8 段切除术。这种新方法似乎是可行的,为伴有门静脉分支肿瘤血栓的 HCC 提供了可靠的解剖学和保守性切除。

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