Faculty of Health Sciences, University of Lethbridge, M3083 Markin Hall, 4401 University Drive, Lethbridge, Alberta, T1K 3M4, Canada.
Department of Mathematical and Statistical Sciences, CAB 632, University of Alberta, Edmonton, Alberta, T6G 2G1, Canada.
Child Abuse Negl. 2020 Mar;101:104348. doi: 10.1016/j.chiabu.2019.104348. Epub 2019 Dec 30.
Binge drinking (BD) is a serious risk factor for fetal alcohol spectrum disorders (FASD) and associated with more severe forms of the disorder. Thus, special attention to specific risk factors for BD adjacent to and during pregnancy is warranted.
(1) To examine the role that maternal adverse childhood experiences (ACEs) may play in BD in the 12 months before pregnancy and during pregnancy in a sample of women with moderate to high socioeconomic status; and (2) to examine the sociodemographic correlates of BD before and during pregnancy within this sample.
This secondary analysis (N = 1663) was derived from the All Our Families prospective cohort study collected in Alberta, Canada between 2008-2011.
Data were collected using three mailed surveys completed by women during and after pregnancy. An established scale examined maternal ACEs before 18 years. Adjusted logistic regression models tested associations between ACE score and BD before and during pregnancy.
Approximately 5 in 10 (48.3 %) and 1 in 10 (10.0 %) women reported ≥1 BD episode before and during pregnancy; respectively. In adjusted models, a woman's ACE score was associated with BD pre-pregnancy in a weak, nonmonotonic fashion; and during pregnancy in a moderate, dose-response fashion. Overall, ACEs resulted in two to three-fold increase in the odds of BD during pregnancy.
Maternal ACEs were common in this middle to upper-middle income, well-educated sample and impacted the next generation through BD in pregnancy. These findings combine with others to speak to the public health significance of maternal ACEs on alcohol-related behaviour among expectant mothers across the socioeconomic spectrum, and the need for targeted evidence-based interventions for this population.
狂饮（BD）是胎儿酒精谱系障碍（FASD）的一个严重风险因素，与该障碍的更严重形式有关。因此，特别需要关注孕妇及其临近孕期的特定BD 风险因素。
（1）在中高社会经济地位的妇女样本中，检验母亲不良童年经历（ACEs）在怀孕前 12 个月和怀孕期间可能对 BD 所起的作用；（2）检验该样本中怀孕前后 BD 的社会人口学相关性。
这是对加拿大阿尔伯塔省于 2008-2011 年间进行的 All Our Families 前瞻性队列研究的二次分析（N=1663）。
数据通过在怀孕期间和之后由女性完成的三个邮寄调查收集。一个成熟的量表检验了母亲 18 岁之前的 ACE。调整后的逻辑回归模型检验了 ACE 评分与怀孕前后 BD 之间的关联。
约有 5 成（48.3%）和 1 成（10.0%）的女性报告在怀孕前和怀孕期间有≥1 次 BD 发作；分别。在调整模型中，女性的 ACE 评分与怀孕前的 BD 呈微弱的非单调关系，与怀孕期间的 BD 呈中等的剂量反应关系。总体而言，ACE 使怀孕期间 BD 的可能性增加了两到三倍。
在这个中到中上收入、受过良好教育的样本中，母亲 ACE 很常见，通过怀孕期间的 BD 影响下一代。这些发现与其他研究相结合，表明 ACE 在整个社会经济范围内对孕妇的酒精相关行为具有公共卫生意义，需要针对这一人群进行有针对性的循证干预。
