Currie Cheryl L, Tough Suzanne C
Faculty of Health Sciences, University of Lethbridge, M3083 Markin Hall, 4401 University Drive, Lethbridge, Alberta, T1K 3M4, Canada.
Cummings School of Medicine, University of Calgary, Calgary, Canada.
BMC Pregnancy Childbirth. 2021 Feb 13;21(1):133. doi: 10.1186/s12884-021-03591-1.
Adverse childhood experiences (ACEs) are associated with illicit drug use among pregnant women who are socioeconomically vulnerable. While it is assumed that the impact of ACEs on illicit drug use in pregnancy is reduced among women with higher socioeconomic status (SES), this assumption is not well tested in the literature. The objective of this study was to examine the impact of maternal ACEs on illicit drug use in a community-based sample of pregnant women with middle to high SES.
This study is a secondary analysis of a prospective cohort study that collected data from 1660 women during and after pregnancy in Calgary, Canada between 2008 and 2011 using mailed surveys. Illicit drug use in pregnancy was self-reported by women at 34-36 weeks gestation. An established scale examined maternal ACEs before 18 years. Logistic regression models and 95% confidence intervals tested associations between maternal ACE scores and illicit drug use in pregnancy.
Overall, 3.1% of women in this predominantly married, well-educated, middle and upper middle income sample reported illicit drug use in pregnancy. Women with 2-3 ACEs had more than a two-fold increase, and women with 4 or more ACEs had almost a four-fold increase in illicit drug use in pregnancy, relative to women with 0-1 ACEs after adjustment for confounders. Exposure to child abuse was more consistently associated with illicit drug use in pregnancy than exposure to household dysfunction in childhood.
Maternal ACEs were common and associated with a moderate increase in the odds of illicit drug use in pregnancy among Canadian women with middle to high SES.
不良童年经历(ACEs)与社会经济弱势的孕妇使用非法药物有关。虽然人们认为,社会经济地位较高(SES)的女性中,ACEs对孕期非法药物使用的影响会降低,但这一假设在文献中并未得到充分验证。本研究的目的是在一个以社区为基础的中高SES孕妇样本中,研究母亲的ACEs对非法药物使用的影响。
本研究是一项前瞻性队列研究的二次分析,该研究于2008年至2011年期间在加拿大卡尔加里,通过邮寄调查问卷的方式,收集了1660名女性孕期及产后的数据。孕期非法药物使用情况由女性在妊娠34 - 36周时自行报告。采用既定量表检查母亲18岁之前的ACEs情况。逻辑回归模型和95%置信区间检验了母亲ACEs得分与孕期非法药物使用之间的关联。
总体而言,在这个以已婚、受过良好教育、中高收入为主的样本中,3.1%的女性报告在孕期使用过非法药物。在调整混杂因素后,与有0 - 1次ACEs的女性相比,有2 - 3次ACEs的女性孕期非法药物使用增加了两倍多,有4次或更多ACEs的女性孕期非法药物使用增加了近四倍。与童年时期家庭功能障碍相比,遭受儿童期虐待与孕期非法药物使用的关联更为一致。
母亲的ACEs很常见,并且与加拿大中高SES女性孕期非法药物使用几率适度增加有关。