Zakharia Kais, Tabibian James H
Internal Medicine Residency Program, Department of Medical Education, Beaumont Health- Dearborn, Dearborn, MI, USA.
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
J Community Med (Reno). 2018;1. doi: 10.33582/2637-4900/1004. Epub 2018 Apr 5.
Infection is the second most common cause of esophagitis, second only to gastroesophageal reflux, and represents a clinically important disorder. Immunosuppressed patients are at highest risk for infectious esophagitis, with herpes simplex virus, and cytomegalovirus being the most common causative microorganisms. Here we provide a brief clinical review and present a case of concomitant oropharyngeal and presumed esophageal candidiasis in a patient with autoimmune hepatitis who was initiated on high-dose corticosteroid therapy and soon thereafter develop odynodysphagia and who was found to have herpes esophagitis diagnosed by endoscopy and histopathology.
感染是食管炎的第二大常见病因，仅次于胃食管反流，是一种具有重要临床意义的疾病。免疫抑制患者发生感染性食管炎的风险最高，单纯疱疹病毒和巨细胞病毒是最常见的致病微生物。在此，我们提供一份简要的临床综述，并介绍一例自身免疫性肝炎患者，该患者开始接受大剂量皮质类固醇治疗后不久出现吞咽痛，随后被内镜检查和组织病理学诊断为疱疹性食管炎，同时伴有口咽念珠菌病和疑似食管念珠菌病。
