Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Graefes Arch Clin Exp Ophthalmol. 2020 Apr;258(4):843-850. doi: 10.1007/s00417-019-04576-9. Epub 2020 Jan 3.
We examined whether a contact lens sensor (CLS) is useful for the postoperative evaluation of trabectome surgery. We investigated the correlations between the outcomes of trabectome surgery and the output of a CLS.
We examined 24 consecutive eyes of patients with pseudo-exfoliation glaucoma. In each eye, the intraocular pressure (IOP) fluctuations over 24 h were measured with the SENSIMED Triggerfish CLS before and at 3 months after the trabectome surgery. We divided the patients into success (n = 12 eyes) and failure (n = 12 eyes) groups; success was defined as a postoperative IOP level ≤ 21 mmHg plus an IOP reduction ≥ 20% relative to the preoperative IOP value with or without anti-glaucoma medications. We investigated CLS parameters that correlate with surgical outcomes by performing a Cox hazard regression analysis. We determined the maximum value, minimum value, and range of IOP fluctuation as CLS parameters.
The mean follow-up period was 38.0 ± 3.0 months. The success rate was 50%. The postoperative range of IOP fluctuation during the nocturnal period with the CLS was significantly correlated with the surgical results (p = 0.024).
A smaller range of IOP fluctuation was significantly correlated with better surgical outcomes. We were able to predict the surgical success after trabectome surgery at 3 months using the CLS. Thus, CLS results could be a new surgical evaluation parameter.
我们研究接触镜传感器（CLS）是否可用于小梁切除术的术后评估。我们调查了小梁切除术结果与 CLS 输出之间的相关性。
我们检查了 24 例患有假性剥脱性青光眼的连续患者的 24 只眼。在每只眼中，使用 SENSIMED Triggerfish CLS 在小梁切除术之前和之后的 3 个月测量了 24 小时内的眼内压（IOP）波动。我们将患者分为成功组（n=12 只眼）和失败组（n=12 只眼）；成功定义为术后眼压水平≤21mmHg，并且与术前眼压值相比，眼压降低≥20%，无论是否使用抗青光眼药物。我们通过进行 Cox 风险回归分析来研究与手术结果相关的 CLS 参数。我们将最大眼压值、最小眼压值和眼压波动范围确定为 CLS 参数。
平均随访期为 38.0±3.0 个月。成功率为 50%。CLS 测量的夜间眼压波动范围与手术结果显著相关（p=0.024）。
眼压波动范围越小，手术结果越好。我们能够使用 CLS 在术后 3 个月预测小梁切除术的手术成功。因此，CLS 结果可能成为新的手术评估参数。
