Wu Kevin Y, Mina Mina, Carbonneau Marjorie, Marchand Michael, Tran Simon D
Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrooke, QC J1G 2E8, Canada.
Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada.
Micromachines (Basel). 2023 Oct 9;14(10):1915. doi: 10.3390/mi14101915.
Glaucoma, marked by its intricate association with intraocular pressure (IOP), stands as a predominant cause of non-reversible vision loss. In this review, the physiological relevance of IOP is detailed, alongside its potential pathological consequences. The review further delves into innovative engineering solutions for IOP monitoring, highlighting the latest advancements in wearable and implantable sensors and their potential in enhancing glaucoma management. These technological innovations are interwoven with clinical practice, underscoring their real-world applications, patient-centered strategies, and the prospects for future development in IOP control. By synthesizing theoretical concepts, technological innovations, and practical clinical insights, this review contributes a cohesive and comprehensive perspective on the IOP biosensor's role in glaucoma, serving as a reference for ophthalmological researchers, clinicians, and professionals.
青光眼与眼内压（IOP）有着复杂的关联，是导致不可逆视力丧失的主要原因。在本综述中，详细阐述了眼内压的生理相关性及其潜在的病理后果。该综述进一步深入探讨了用于眼内压监测的创新工程解决方案，重点介绍了可穿戴和植入式传感器的最新进展及其在改善青光眼管理方面的潜力。这些技术创新与临床实践紧密结合，强调了它们在现实世界中的应用、以患者为中心的策略以及眼内压控制的未来发展前景。通过综合理论概念、技术创新和实际临床见解，本综述为眼内压生物传感器在青光眼中的作用提供了一个连贯而全面的视角，可供眼科研究人员、临床医生和专业人士参考。
