Funahashi K
Department of Neurological Surgery, Wakayama Medical College, Japan.
No To Shinkei. 1988 Sep;40(9):841-8.
The clinical features of congenital nystagmus (CN) were studied statistically in 106 cases of CN. The point of the nystagmus at which the patients could best see the targets was detected in some patients. The effects of superior colliculectomy on their visual disturbance and the mechanism will be discussed. The study population comprises 106 patients, 79 males and 27 females, aged from one to 64 (mean 19.4 years). Patients with jerky type classified on ENG were found in 53 cases (50%), pendular type in 39 cases (37%), and mixed type in 14 cases (13%). Patients with jerky type showed significantly good visual acuity (mean 0.69 +/- 0.31, p less than 0.005). They showed significant abnormalities during pregnancy and delivery (p less than 0.01) and had a neutral point (p less than 0.01). Patients with pendular type, on the other hand, showed poor visual acuity (mean 0.26 +/- 0.30) and had significant frequency of family history (p less than 0.05), head tremor (p less than 0.01) and strabismus (p less than 0.01). Thirteen cases (12%) had ocular diseases which involved the retina, cornea and optic nerve. Visual function was elaborated on such parameters of ENG as perception, peak variation and plateau time. Perception, which means the ability to detect the dim flashes during the appearance of the nystagmus, was manifested by pushing a button when patients could detect flashes presented at random on the screen. At the turning point from the quick phase to the slow phase, the detection was executed most successfully. It is thought that in CN, a target is usually gazed upon at a point, changing the direction from the quick phase to the slow phase.(ABSTRACT TRUNCATED AT 250 WORDS)
对106例先天性眼球震颤（CN）患者的临床特征进行了统计学研究。部分患者检测出了眼球震颤时患者能最佳视物的点。将讨论上丘切除术对其视觉障碍的影响及机制。研究对象包括106例患者，其中男性79例，女性27例，年龄从1岁至64岁（平均19.4岁）。根据眼震电图（ENG）分类，急跳型患者53例（50%），钟摆型39例（37%），混合型14例（13%）。急跳型患者视力显著较好（平均0.69±0.31，p<0.005）。他们在妊娠和分娩期间有显著异常（p<0.01）且有中性点（p<0.01）。另一方面，钟摆型患者视力较差（平均0.26±0.30），家族史、头部震颤（p<0.01）和斜视（p<0.01）的发生率显著较高。13例（12%）患有累及视网膜、角膜和视神经的眼部疾病。根据ENG的感知、峰值变化和平台期等参数详细阐述了视觉功能。感知是指在眼球震颤出现时检测微弱闪光的能力，当患者能检测到屏幕上随机出现的闪光时通过按按钮来体现。在从快相到慢相的转折点，检测最为成功。据认为，在先天性眼球震颤中，通常在一个点注视目标，方向从快相变为慢相。（摘要截断于250字）
