College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou, 310018, China.
School of Geography and Ocean Science, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210023, China.
Chemosphere. 2020 May;246:125764. doi: 10.1016/j.chemosphere.2019.125764. Epub 2019 Dec 28.
Some polycyclic aromatic hydrocarbons (PAHs) are carcinogenic and mutagenic to humans. However, little is known about PAH exposure to people living in urban and suburban areas through comparative studies. Some studies have indicated that human hair can be used as a noninvasive biomarker of PAH exposure. Therefore, we collected hair samples from 66 volunteers from Nanjing and Ningbo, China, to detect PAH concentrations in this work. The highest levels in the hair samples were found in phenanthrene > anthracene > naphthalene among the parent PAHs. Sixteen parent PAHs showed higher concentrations in the samples from Nanjing than in the samples from Ningbo. Significantly higher levels of some PAHs were observed in male hair than in female hair in Nanjing, and in hair from smokers than in hair from non-smokers in both Nanjing and Ningbo. In addition, there was a significant effect of the age on the concentration of low-molecular-weight PAHs and ∑PAHs in human hair in both Nanjing and Ningbo. Studying the inter-chemical associations between these PAHs indicated similarities and differences between Nanjing and Ningbo.
一些多环芳烃（PAHs）对人类具有致癌性和致突变性。然而，通过比较研究，人们对生活在城市和郊区的人群中多环芳烃的暴露情况知之甚少。一些研究表明，人类头发可用作多环芳烃暴露的非侵入性生物标志物。因此，我们从中国南京和宁波的 66 名志愿者身上采集了头发样本，以检测这些工作中的多环芳烃浓度。在母体多环芳烃中，发样中苊烯>蒽>萘的浓度最高。在南京的发样中，十六种母体多环芳烃的浓度高于宁波的发样。在南京，男性头发中的某些多环芳烃水平明显高于女性，在南京和宁波，吸烟者头发中的某些多环芳烃水平明显高于不吸烟者。此外，南京和宁波的低分子量多环芳烃和∑多环芳烃在头发中的浓度均受年龄的显著影响。研究这些多环芳烃之间的化学关联表明，南京和宁波之间存在相似和差异。
