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对有助于健康的海洋资源成分的健康益处和生物利用度的研究

Health benefits and bioavailability of marine resources components that contribute to health

机构信息

Universidade Católica Portuguesa, CBQF - Centro de Biotecnlogia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Porto, Portugal.

Allmicroalgae - Natural Products Avenida Duarte Pacheco, Lisboa, Portugal.

出版信息

Crit Rev Food Sci Nutr. 2020;60(21):3680-3692. doi: 10.1080/10408398.2019.1704681. Epub 2020 Jan 10.

Abstract

The strict connection between nutritional intake and health leads to a necessity of understanding the beneficial and protective role of healthy nutrients and foods. The marine environment is a source of a plethora of many organisms with unique properties, extremely rich in bioactive compounds and with remarkable potential for medical, industrial and biotechnological applications. Marine organisms are an extreme valuable source of functional ingredients such as polysaccharides, vitamins, minerals, pigments, enzymes, proteins and peptides, polyunsaturated fatty acids (PUFA), phenolic compounds and other secondary metabolites that prevent or have the potential to treat several diseases given their cardiovascular protective, anti-inflammatory, anti-hypertensive, anti-oxidant, anti-coagulant, anti-proliferative and anti-diabetic activities. This review provides an overview on the current advances regarding health benefits of marine bioactive compounds on several diseases and on human gut microbiota. In addition, it is discussed a crucial factor that is related to the effectiveness of these compounds on human organism namely its real bioavailability.

摘要

营养摄入与健康之间的紧密联系使得我们有必要了解健康营养物质和食物的有益和保护作用。海洋环境是许多具有独特特性的生物体的丰富来源,这些生物体富含生物活性化合物,具有显著的医学、工业和生物技术应用潜力。海洋生物是功能成分的极具价值的来源,如多糖、维生素、矿物质、色素、酶、蛋白质和肽、多不饱和脂肪酸 (PUFA)、酚类化合物和其他次级代谢物,由于它们具有心血管保护、抗炎、抗高血压、抗氧化、抗凝血、抗增殖和抗糖尿病的活性,这些成分可以预防或有可能治疗多种疾病。本综述概述了海洋生物活性化合物对多种疾病和人类肠道微生物群的健康益处的最新进展。此外,还讨论了与这些化合物对人体有效性相关的一个关键因素,即它们的实际生物利用度。

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