Fisher P, Gatterer G, Danielczyk W
Neurological Institute, Vienna Medical School, Geriatric Hospital Lainz, Austria.
Funct Neurol. 1988 Jul-Sep;3(3):301-7.
Previous studies found the semantic system particularly affected in Dementia of Alzheimer's Type (DAT), which would have important implications for the clinical diagnosis of this disease. We compared 14 non-demented parkinsonian patients and 14 controls on one hand and demented patients suffering from multi-infarct dementia (n = 17), DAT (n = 18) and Parkinsonism + dementia (n = 7) on the other. Demented groups were well matched regarding severity of dementia. Two tasks of semantic memory (naming, word fluency) did not differentiate within demented groups, but were correlated with severity of dementia.
先前的研究发现,语义系统在阿尔茨海默病型痴呆(DAT)中受到的影响尤为显著,这对该疾病的临床诊断具有重要意义。一方面,我们比较了14名非痴呆帕金森病患者和14名对照者;另一方面,比较了患有多发梗死性痴呆(n = 17)、DAT(n = 18)和帕金森病合并痴呆(n = 7)的痴呆患者。各痴呆组在痴呆严重程度方面匹配良好。两项语义记忆任务(命名、词语流畅性)在痴呆组内部没有差异,但与痴呆严重程度相关。