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Why the Therapeutic Impact of RAS Mutation Clearance in Plasma ctDNA Deserves to Be Further Explored in Metastatic Colorectal Cancer.

作者信息

Nicolazzo Chiara, Belardinilli Francesca, Caponnetto Salvatore, Gradilone Angela, Cortesi Enrico, Giannini Giuseppe, Gazzaniga Paola

机构信息

Liquid Biopsy Unit, Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

出版信息

Front Oncol. 2019 Dec 17;9:1414. doi: 10.3389/fonc.2019.01414. eCollection 2019.

DOI:10.3389/fonc.2019.01414
PMID:31921671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6933952/
Abstract
摘要

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本文引用的文献

1
EGFR Inhibitor as Second-Line Therapy in a Patient With Mutant Metastatic Colorectal Cancer: Circulating Tumor DNA to Personalize Treatment.表皮生长因子受体抑制剂作为一名转移性结直肠癌突变患者的二线治疗：利用循环肿瘤DNA实现个性化治疗
JCO Precis Oncol. 2018 Nov;2:1-6. doi: 10.1200/PO.17.00277.
2
Circulating Tumor DNA Analysis in Colorectal Cancer: From Dream to Reality.结直肠癌中的循环肿瘤DNA分析：从梦想走向现实
JCO Precis Oncol. 2019 Dec;3:1-14. doi: 10.1200/PO.18.00397.
3
Correlation Between Tumor-Specific Mutated and Methylated DNA in Colorectal Cancer.结直肠癌中肿瘤特异性突变DNA与甲基化DNA的相关性
JCO Precis Oncol. 2019 Dec;3:1-8. doi: 10.1200/PO.18.00162.
4
Plasma clearance of RAS mutation under therapeutic pressure is a rare event in metastatic colorectal cancer.在治疗压力下，RAS突变的血浆清除在转移性结直肠癌中是一种罕见事件。
Int J Cancer. 2020 Aug 15;147(4):1185-1189. doi: 10.1002/ijc.32657. Epub 2019 Oct 12.
5
How liquid biopsies can change clinical practice in oncology.液体活检如何改变肿瘤学的临床实践。
Ann Oncol. 2019 Oct 1;30(10):1580-1590. doi: 10.1093/annonc/mdz227.
6
Comparison of the Clinical Sensitivity of the Idylla Platform and the OncoBEAM RAS CRC Assay for KRAS Mutation Detection in Liquid Biopsy Samples.对比液活检样本中 Idylla 平台与 OncoBEAM RAS CRC 检测试剂盒检测 KRAS 基因突变的临床灵敏度。
Sci Rep. 2019 Jun 20;9(1):8976. doi: 10.1038/s41598-019-45616-y.
7
Roles of Methylated DNA Biomarkers in Patients with Colorectal Cancer.甲基化 DNA 生物标志物在结直肠癌患者中的作用。
Dis Markers. 2019 Mar 3;2019:2673543. doi: 10.1155/2019/2673543. eCollection 2019.
8
Systemic treatment for metastatic colorectal cancer in the era of precision medicine.精准医学时代转移性结直肠癌的全身治疗
J Surg Oncol. 2019 Apr;119(5):564-582. doi: 10.1002/jso.25421. Epub 2019 Feb 25.
9
Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer.血浆中RAS突变克隆的短暂消失：EGFR抑制剂在RAS突变型转移性结直肠癌中的一种违反直觉的临床应用
Cancers (Basel). 2019 Jan 4;11(1):42. doi: 10.3390/cancers11010042.
10
Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.转移性结直肠癌的分子亚型与治疗决策的演变
Am Soc Clin Oncol Educ Book. 2018 May 23;38:231-238. doi: 10.1200/EDBK_200929.