胃侵袭性纤维瘤病：1例报告并文献复习
Gastric aggressive fibromatosis: report of a case and review of the literature.
作者信息
Wang Yang-Kun, Jiang Bo, Yang Yan-Cheng, Wang Su-Nan, Li Ying-Ying, Meng Nian-Long, Yuan Xu-Tao, Jiang Run-De, Li Zu-Guo
机构信息
Department of Pathology, Southern Medical University Shenzhen Hospital Shenzhen, Guangdong, China.
Department of Pathology, 159 Hospital of PLA Zhumadian, China.
出版信息
Int J Clin Exp Pathol. 2019 Jan 1;12(1):372-377. eCollection 2019.
OBJECTIVES
To describe a rare case of aggressive fibromatosis of the stomach and discuss the differential diagnoses.
METHODS
A 47-year-old man presented with nonspecific abdominal pain. Gastroscopy revealed stomach wall swelling. An antral gastrectomy was performed. Histological examination revealed spindle-shaped cells and morphology typical of aggressive fibromatosis. We performed a literature search to identify conditions with features similar to those of aggressive fibromatosis.
RESULTS
Aggressive fibromatosis does not metastasize, but it is locally invasive and has a tendency to relapse; however, our patient has not had recurrence > 1 year after surgery. Aggressive fibromatosis of the stomach may be confused with an inflammatory fibroid polyp, a gastrointestinal stromal tumor, schwannoma, leiomyoma, inflammatory myofibroblastic tumor, scirrhous carcinoma of the stomach, follicular dendritic cell sarcoma, inflammatory malignant fibrous histiocytoma, myofibroma/myofibromatosis, and solitary fibrous tumor of the stomach.
CONCLUSIONS
Aggressive fibromatosis of the stomach is a rare spindle cell tumor that must be differentiated from a variety of conditions.
目的
描述一例罕见的胃部侵袭性纤维瘤病病例并讨论鉴别诊断。
方法
一名47岁男性因非特异性腹痛就诊。胃镜检查显示胃壁肿胀。实施了胃窦切除术。组织学检查发现梭形细胞以及侵袭性纤维瘤病典型的形态学特征。我们进行了文献检索以确定具有与侵袭性纤维瘤病相似特征的疾病。
结果
侵袭性纤维瘤病不会发生转移，但具有局部侵袭性且有复发倾向；然而，我们的患者术后1年多未复发。胃部侵袭性纤维瘤病可能会与炎性纤维性息肉、胃肠道间质瘤、神经鞘瘤、平滑肌瘤、炎性肌纤维母细胞瘤、胃硬癌、滤泡树突状细胞肉瘤、炎性恶性纤维组织细胞瘤、肌纤维瘤/肌纤维瘤病以及胃部孤立性纤维瘤相混淆。
结论
胃部侵袭性纤维瘤病是一种罕见的梭形细胞肿瘤，必须与多种疾病进行鉴别。
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