Centre for Human Exposure Science, Institute of Occupational Medicine, Edinburgh EH14 4AP, UK.
Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot Watt University, Edinburgh EH14 4AS, UK.
Int J Environ Res Public Health. 2020 Jan 7;17(2):383. doi: 10.3390/ijerph17020383.
Model tools for estimating hazardous substance exposure are an accepted part of regulatory risk assessments in Europe, and models underpin control banding tools used to help manage chemicals in workplaces. Of necessity the models are simplified abstractions of real-life working situations that aim to capture the essence of the scenario to give estimates of actual exposures with an appropriate margin of safety. The basis for existing inhalation exposure assessment tools has recently been discussed by some scientists who have argued for the use of more complex models. In our opinion, the currently accepted tools are documented to be the most robust way for workplace health and safety practitioners and others to estimate inhalation exposure. However, we recognise that it is important to continue the scientific development of exposure modelling to further elaborate and improve the existing methodologies.
用于估算有害物质暴露的模型工具是欧洲监管风险评估的公认组成部分，模型也是用于帮助管理工作场所化学品的控制带工具的基础。这些模型必然是对现实工作情况的简化抽象，旨在捕捉场景的本质，以给出具有适当安全裕度的实际暴露估计。最近，一些科学家讨论了现有吸入暴露评估工具的基础，他们主张使用更复杂的模型。在我们看来，目前被接受的工具被证明是工作场所健康和安全从业者以及其他人估算吸入暴露的最可靠方法。然而，我们认识到继续进行暴露建模的科学发展以进一步阐述和改进现有方法学非常重要。
