Khan Adnan, Khan Muhammad Zahoor, Umer Saqib, Khan Ibrar Muhammad, Xu Huitao, Zhu Huabin, Wang Yachun
National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Embryo Biotechnology and Reproduction Laboratory, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Animals (Basel). 2020 Jan 9;10(1):110. doi: 10.3390/ani10010110.
Heat stress has long been recognized as a challenging issue that severely influences the reproductive functions of dairy cattle, disrupting oocyte development during fetal growth. These detrimental effects of heat stress are the result of either the hyperthermia associated with heat stress or the physiological adjustments made by the heat-stressed animal to regulate body temperature. In addition, elevated temperatures have been implicated in increasing the production of reactive oxygen species. Thus, understanding the impact of heat stress on reproductive functions, from a cellular to molecular level, might help in selecting heat-resilient dairy cattle and developing heat stress mitigation strategies. In the present paper, we have attempted to describe the changes in the reproductive system and function of dairy cattle in response to heat stress by reviewing the latest literature in this area. The review provides useful knowledge on the cellular and genetic basis of oocyte and granulosa cells in heat-stressed dairy cattle, which could be helpful for future research in this area.
长期以来，热应激一直被认为是一个具有挑战性的问题，它严重影响奶牛的繁殖功能，在胎儿生长期间扰乱卵母细胞发育。热应激的这些有害影响是热应激相关的体温过高或热应激动物为调节体温而进行的生理调整的结果。此外，高温还与活性氧的产生增加有关。因此，从细胞到分子水平了解热应激对繁殖功能的影响，可能有助于选择耐热性强的奶牛并制定减轻热应激的策略。在本文中，我们试图通过回顾该领域的最新文献来描述奶牛生殖系统和功能对热应激的反应变化。该综述提供了关于热应激奶牛卵母细胞和颗粒细胞的细胞和遗传基础的有用知识，这可能有助于该领域的未来研究。
