Departamento de Fisiologia e Biofísica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
Departamento de Pediatria, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
J Bras Nefrol. 2020 Mar;42(1):67-76. doi: 10.1590/2175-8239-JBN-2018-0213. Epub 2020 Jan 10.
Despite the current availability of safe and efficient drugs for treating hypertension, a substantial number of patients are drug-resistant hypertensives. Aiming this condition, a relatively new approach named catheter-based renal denervation was developed. We have now a clinically relevant time window to review the efficacy of renal denervation for treating this form of hypertension. This short review addresses the physiological contribution of renal sympathetic nerves for blood pressure control and discusses the pros and cons of renal denervation procedure for the treatment of resistant hypertension.
尽管目前有安全有效的药物可用于治疗高血压，但仍有相当数量的患者为耐药性高血压患者。针对这种情况，开发了一种名为基于导管的肾脏去神经支配的新方法。现在我们有一个临床相关的时间窗口来回顾肾脏去神经支配治疗这种高血压形式的疗效。这篇简短的综述讨论了肾脏交感神经对血压控制的生理贡献，并讨论了肾脏去神经支配手术治疗耐药性高血压的优缺点。
