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[倍他米松的精神作用(作者译)]

[The psychotropic effect of beclamid (author's transl)].

作者信息

Menz W, Tschernutter K, Rohrbach G

出版信息

Padiatr Padol. 1977;12(1):85-9.

PMID:319408
Abstract

60 boys and girls between 6 and 14 years with the symptoms "psychomotoric unrest", "disturbance of behavior" and "disturbed concentration" with and without epilepsy were treated and observed in hospital during a period of 8 weeks. Group I (20 patients) was given Beclamid, 3--6 tablets a day according to weight. Group II (20 patients) was given placebos in the same dosage. Group III (20 patients) was given Beclamid during 4 weeks and placebo for the following 4 weeks. Compared with the placebo groups the influence on concentration, memory and skill was significantly better after the application of Beclamid. The extent of the improvement depended on the period of medication. The Beclamid-group could be guided more easily, showed a better sense for cooperation and turned out to be more accessable to pedagogic methods. This positive psychotropic effect again increased with the period of medication. The (positive) influence on behaviour also affected the effciency at shcool and learning. Neither a sedative nor other side effects could be seen.

摘要

60名6至14岁有“精神运动性不安”、“行为障碍”和“注意力不集中”症状的男孩和女孩,无论有无癫痫,在医院接受了为期8周的治疗和观察。第一组(20名患者)根据体重每天服用3至6片倍氯米松。第二组(20名患者)服用相同剂量的安慰剂。第三组(20名患者)服用倍氯米松4周,接下来4周服用安慰剂。与安慰剂组相比,服用倍氯米松后对注意力、记忆力和技能的影响明显更好。改善程度取决于用药时间。倍氯米松组更容易被引导,表现出更好的合作意识,并且对教学方法的接受度更高。这种积极的精神otropic作用随着用药时间再次增强。对行为的(积极)影响也影响了在学校的效率和学习。未观察到镇静作用或其他副作用。

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