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[额叶病变导致的精神自我激活丧失和刻板的精神活动。与强迫症的关系]

[Loss of psychic self-activation and stereotyped mental activity caused by a frontal lesion. Relation of the obsessive-compulsive disorder].

作者信息

Laplane D, Dubois B, Pillon B, Baulac M

机构信息

Service de Neurologie, Hôpital de la Salpêtrière, Paris.

出版信息

Rev Neurol (Paris). 1988;144(10):564-70.

PMID:3194604
Abstract

A case of frontal lobe lesions is reported, its interest being that it is similar to a syndrome that we have previously described as the consequence of lenticular nucleus lesions. This syndrome includes primarily a loss of psychic self-activation (psychic akinesia) and compulsive or pseudo-compulsive activities. In the present case the lesions involved the deep white matter of the prefrontal cortex on both sides, and were most extensive in the depth of the middle frontal gyrus. This similitude brings further support to the notion that subcortical damage of the lenticular nuclei can induce a frontal-like syndrome. The similitude with some of the behavioural aspects or depressive of hebephrenic states is emphasized. The occurrence of stereotyped mental activities is the basis for a discussion of the relationships with some features of obsessive-compulsive neurosis.

摘要

本文报告了一例额叶病变病例,其有趣之处在于它类似于我们之前描述的一种综合征,该综合征是豆状核病变的结果。该综合征主要包括精神自我激活丧失(精神运动不能)以及强迫或类强迫活动。在本病例中,病变累及双侧前额叶皮质深层白质,在额中回深部最为广泛。这种相似性进一步支持了豆状核的皮质下损伤可诱发类额叶综合征这一观点。文中强调了与青春型精神分裂症某些行为方面或抑郁症状的相似性。刻板心理活动的出现为讨论与强迫性神经症某些特征的关系提供了依据。

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