Shteĭnberg L Sh, Dorofeeva L V, Zasorina I N, Barkova E P, Boriskin Iu S
Vopr Virusol. 1988 Jul-Aug;33(4):465-9.
Magnesium sulphate in concentrations of 25-50 mM induced reproducible increase in titers of extracellular measles virus (by 0.5-2.0 1g TCD50/0.5 ml) in Japanese quail embryo cells. MgSO4 effect was observed with all methods of cell cultivation: stationary, roller, or on microcarriers. Its effect was associated not with its stabilizing influence on the extracellular virus but rather with the stimulation of the synthesis of intracellular viral proteins.
浓度为25 - 50 mM的硫酸镁可使日本鹌鹑胚胎细胞中细胞外麻疹病毒滴度产生可重复的增加(增加0.5 - 2.0 1g TCD50/0.5 ml)。在所有细胞培养方法中均观察到了硫酸镁的作用:静止培养、旋转培养或在微载体上培养。其作用并非与其对细胞外病毒的稳定作用相关,而是与刺激细胞内病毒蛋白的合成有关。