Zhu Lynn, Duval Christian, Boissy Patrick, Montero-Odasso Manuel, Zou Guangyong, Jog Mandar, Speechley Mark
Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Rotman Research Institute, Baycrest Health Sciences, Toronto, Ontario, Canada.
J Gerontol A Biol Sci Med Sci. 2020 Nov 13;75(12):2361-2370. doi: 10.1093/gerona/glaa012.
Real-life community mobility (CM) measures for older adults, especially those with Parkinson's disease (PD), are important tools when helping individuals maintain optimal function and quality of life. This is one of the first studies to compare an objective global positioning system (GPS) sensor and subjective self-report CM measures in an older clinical population.
Over 14 days, 54 people in Ontario, Canada with early to mid-stage PD (mean age = 67.5 ± 6.3 years; 47 men; 46 retired) wore a wireless inertial measurement unit with GPS (WIMU-GPS), and completed the Life Space Assessment and mobility diaries. We assessed the convergent validity, reliability and agreement on mobility outcomes using Spearman's correlation, intraclass correlation coefficient, and Bland-Altman analyses, respectively.
Convergent validity was attained by the WIMU-GPS for trip frequency (rs = .69, 95% confidence interval [CI] = 0.52-0.81) and duration outside (rs = .43, 95% CI = 0.18-0.62), but not for life space size (rs = .39, 95% CI = 0.14-0.60). The Life Space Assessment exhibited floor and ceiling effects. Moderate agreements were observed between WIMU-GPS and diary for trip frequency and duration (intraclass correlation coefficients = 0.71, 95% CI = 0.51-0.82; 0.67, 95% CI = 0.42-0.82, respectively). Disagreement was more common among nonretired individuals.
WIMU-GPS could replace diaries for trip frequency and duration assessments in older adults with PD. Both assessments are best used for retired persons. However, the Life Space Assessment may not reflect actual mobility.
现实生活中老年人的社区活动能力(CM)测量,尤其是帕金森病(PD)患者的,是帮助个体维持最佳功能和生活质量的重要工具。这是首批在老年临床人群中比较客观的全球定位系统(GPS)传感器测量与主观自我报告的CM测量的研究之一。
在14天内,加拿大安大略省的54名早中期PD患者(平均年龄 = 67.5 ± 6.3岁;47名男性;46名退休人员)佩戴了带有GPS的无线惯性测量单元(WIMU-GPS),并完成了生活空间评估和活动日记。我们分别使用斯皮尔曼相关性分析、组内相关系数分析和布兰德 - 奥特曼分析来评估活动结果的收敛效度、信度和一致性。
WIMU-GPS在出行频率(rs = 0.69,95%置信区间[CI] = 0.52 - 0.81)和户外停留时间(rs = 0.43,95% CI = 0.18 - 0.62)方面达到了收敛效度,但在生活空间大小方面未达到(rs = 0.39,95% CI = 0.14 - 0.60)。生活空间评估显示出地板效应和天花板效应。WIMU-GPS与日记在出行频率和持续时间方面观察到中等一致性(组内相关系数分别为0.71,95% CI = 0.51 - 0.82;0.67,95% CI = 0.42 - 0.82)。不一致在未退休个体中更常见。
WIMU-GPS可替代日记用于PD老年患者的出行频率和持续时间评估。两种评估方法最适合退休人员。然而,生活空间评估可能无法反映实际活动能力。