Department of Psychology, Macquarie University, Sydney, Australia.
Memory. 2020 Mar;28(3):323-336. doi: 10.1080/09658211.2020.1713379. Epub 2020 Jan 20.
Music is highly efficient at evoking autobiographical memories in both healthy and neurological populations. Music evoked autobiographical memories (MEAMs) are preserved in people with Alzheimer's Dementia (AD), and occur at the same frequency as in healthy people. To date there has been no investigation of the integrity of MEAMs in people with non-AD dementia. This study provides the first characterisation of the frequency and specificity of MEAMs and photo evoked autobiographical memories (PEAMs) in 6 people with Behavioural variant frontotemporal dementia (Bv-FTD). We found significantly reduced frequency and specificity of MEAMs and PEAMs in people with Bv-FTD compared with healthy elderly. This supports the known decline in autobiographical memory function in this population, and the integral role of medial frontal regions in the retrieval of MEAMs. Our findings highlight that the mnemonic effects of music vary between people with different types of dementia, which has implications for dementia care.
音乐在健康人群和神经人群中都非常有效地唤起自传体记忆。阿尔茨海默病（AD）患者保留了音乐唤起的自传体记忆（MEAMs），其发生频率与健康人群相同。迄今为止，尚无研究探讨非 AD 痴呆患者 MEAMs 的完整性。本研究首次对 6 名行为变异额颞叶痴呆（Bv-FTD）患者的 MEAMs 和照片唤起的自传体记忆（PEAMs）的频率和特异性进行了特征描述。与健康老年人相比，Bv-FTD 患者的 MEAMs 和 PEAMs 频率和特异性显著降低。这支持了该人群自传体记忆功能的已知下降，以及内侧额叶区域在 MEAMs 检索中的整体作用。我们的研究结果表明，不同类型痴呆患者的音乐记忆效果不同，这对痴呆症护理具有重要意义。
