Emerg Infect Dis. 2020 Feb;26(2):191-198. doi: 10.3201/eid2602.190697.
Middle East respiratory syndrome coronavirus (MERS-CoV) infection causes a spectrum of respiratory illness, from asymptomatic to mild to fatal. MERS-CoV is transmitted sporadically from dromedary camels to humans and occasionally through human-to-human contact. Current epidemiologic evidence supports a major role in transmission for direct contact with live camels or humans with symptomatic MERS, but little evidence suggests the possibility of transmission from camel products or asymptomatic MERS cases. Because a proportion of case-patients do not report direct contact with camels or with persons who have symptomatic MERS, further research is needed to conclusively determine additional mechanisms of transmission, to inform public health practice, and to refine current precautionary recommendations.
中东呼吸综合征冠状病毒(MERS-CoV)感染可引起从无症状到轻症再到重症的一系列呼吸道疾病。MERS-CoV 偶尔会在人与人之间通过人际接触传播,并且会从单峰驼零星传播给人类。目前的流行病学证据支持直接接触有症状的 MERS 骆驼或人类是主要的传播途径,但几乎没有证据表明从骆驼产品或无症状 MERS 病例传播的可能性。由于一部分病例患者没有报告与骆驼或有症状的 MERS 患者直接接触,因此需要进一步研究来确定其他传播机制,为公共卫生实践提供信息,并完善当前的预防建议。