Sarant Julia, Harris David, Busby Peter, Maruff Paul, Schembri Adrian, Lemke Ulrike, Launer Stefan
Department of Audiology and Speech Pathology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Department of Economics, The University of Melbourne, Melbourne, Victoria 3010, Australia.
J Clin Med. 2020 Jan 17;9(1):254. doi: 10.3390/jcm9010254.
Hearing loss is a modifiable risk factor for dementia in older adults. Whether hearing aid use can delay the onset of cognitive decline is unknown. Participants in this study (aged 62-82 years) were assessed before and 18 months after hearing aid fitting on hearing, cognitive function, speech perception, quality of life, physical activity, loneliness, isolation, mood, and medical health. At baseline, multiple linear regression showed hearing loss and age predicted significantly poorer executive function performance, while tertiary education predicted significantly higher executive function and visual learning performance. At 18 months after hearing aid fitting, speech perception in quiet, self-reported listening disability and quality of life had significantly improved. Group mean scores across the cognitive test battery showed no significant decline, and executive function significantly improved. Reliable Change Index scores also showed either clinically significant improvement or stability in executive function for 97.3% of participants, and for females for working memory, visual attention and visual learning. Relative stability and clinically and statistically significant improvement in cognition were seen in this participant group after 18 months of hearing aid use, suggesting that treatment of hearing loss with hearing aids may delay cognitive decline. Given the small sample size, further follow up is required.
听力损失是老年人患痴呆症的一个可改变的风险因素。使用助听器是否能延缓认知能力下降的发生尚不清楚。本研究的参与者(年龄在62 - 82岁之间)在佩戴助听器之前和之后18个月接受了听力、认知功能、言语感知、生活质量、身体活动、孤独感、社交隔离、情绪和身体健康方面的评估。在基线时,多元线性回归显示听力损失和年龄预示着执行功能表现显著较差,而高等教育预示着执行功能和视觉学习表现显著较高。在佩戴助听器18个月后,安静环境下的言语感知、自我报告的听力残疾和生活质量有显著改善。整个认知测试组的组平均分数没有显著下降,执行功能显著改善。可靠变化指数分数还显示,97.3%的参与者在执行功能方面有临床显著改善或稳定,女性在工作记忆、视觉注意力和视觉学习方面也是如此。在使用助听器18个月后,该参与者组在认知方面呈现出相对稳定性以及临床和统计学上的显著改善,这表明使用助听器治疗听力损失可能会延缓认知能力下降。鉴于样本量较小,需要进一步随访。