Department of Pediatrics, Hospital Group Twente, 17609 PP Almelo, The Netherlands.
Department of BMS, University Twente, 57522 NB Enschede, The Netherlands.
Nutrients. 2020 Jan 20;12(1):272. doi: 10.3390/nu12010272.
Since no treatment exists for children suffering from upper respiratory tract infections (URTIs) without immunological disorders, we searched for a possible tool to improve the health of these children.
We evaluated whether dietary advice (based on food matrix and food synergy), including standard supportive care, can decrease the number and duration of URTIs in children with recurrent URTIs.
This study was a multicenter randomized controlled trial in two pediatric outpatient clinics in the Netherlands, with 118 children aged one to four years with recurrent URTIs. The dietary advice group received dietary advice plus standard supportive care, while the control group received standard supportive care alone for six months. The dietary advice consisted of green vegetables five times per week, beef three times per week, 300 mL whole milk per day, and whole dairy butter on bread every day. Portion sizes were age-appropriate.
Children in the dietary advice group had 4.8 (1.6-9.5) days per month with symptoms of an URTI in the last three months of the study, compared to 7.7 (4.0-12.3) in the control group ( = 0.028). The total number of URTIs during the six-month study period was 5.7 (0.55) versus 6.8 (0.49), respectively ( = 0.068). The use of antibiotics was significantly reduced in the dietary advice group, as well as visits to a general practitioner, thereby possibly reducing healthcare costs. The results show a reduced number of days with symptoms of a URTI following dietary advice. The number of infections was not significantly reduced.
由于对于没有免疫障碍的上呼吸道感染（URTIs）患儿，目前还没有治疗方法，因此我们寻求一种可能的工具来改善这些患儿的健康状况。
我们评估了饮食建议（基于食物基质和食物协同作用），包括标准的支持性护理，是否可以减少患有复发性 URTIs 的儿童的 URTIs 的数量和持续时间。
这是一项在荷兰两家儿科门诊进行的多中心随机对照试验，共有 118 名 1 至 4 岁的复发性 URTIs 患儿参与。饮食建议组接受饮食建议加标准支持性护理，而对照组仅接受标准支持性护理 6 个月。饮食建议包括每周五次食用绿色蔬菜、每周三次食用牛肉、每天 300 毫升全脂牛奶以及每天在面包上涂抹全脂奶油。食用份量适合年龄。
与对照组相比，在研究的最后三个月中，饮食建议组的儿童每月有 4.8（1.6-9.5）天出现 URTI 症状，而对照组为 7.7（4.0-12.3）天（=0.028）。在六个月的研究期间，URTIs 的总次数分别为 5.7（0.55）和 6.8（0.49）（=0.068）。饮食建议组抗生素的使用以及就诊普通科医生的次数明显减少，从而可能降低医疗保健费用。结果表明，饮食建议后 URTI 症状的天数减少。感染的数量没有明显减少。
