Kolarević Vjekoslav, Vidaković Ivan, Šutalo Marko, Rapan Vjeran, Rapan Domagoj, Rapan Saša
1Department of Orthopedics, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 2One Health Group, Sheffield, United Kingdom; 3Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Acta Clin Croat. 2019 Sep;58(3):523-528. doi: 10.20471/acc.2019.58.03.17.
The aim of this study was to compare and evaluate clinical results before and after vertebroplasty in the treatment of myeloma-induced vertebral fractures. Success of the surgery was defined by increased or reduced pain intensity before and after the treatment, as assessed using the visual analog scale (VAS). The study was designed as a retrospective-prospective study. The study included 26 patients, 14 women and 12 men. Data on patients treated for myeloma-induced vertebral fractures were collected at the Department of Orthopedics, Osijek University Hospital Centre. The following data were analyzed: gender, duration of illness, intensity of pain before and after treatment (using VAS), radiological changes before and after treatment, grade of vertebral fracture, and extracorporeal cement leakage from the vertebral body to the surrounding tissue during the procedure. Difference in pain intensity before and after the surgery was statistically significant. All patients complained of pain before the surgery (pain intensity median 8), whereas after the surgery, pain intensity decreased in all patients (pain intensity median 2). In conclusion, improvement in clinical results of the treatment of myeloma-induced vertebral fractures with vertebroplasty proved to be significant.
本研究的目的是比较和评估椎体成形术治疗骨髓瘤所致椎体骨折前后的临床效果。手术成功的定义为治疗前后疼痛强度增加或降低，采用视觉模拟量表（VAS）进行评估。本研究设计为回顾性-前瞻性研究。该研究纳入了26例患者，其中女性14例，男性12例。在奥西耶克大学医院中心骨科收集了骨髓瘤所致椎体骨折患者的治疗数据。分析了以下数据：性别、病程、治疗前后的疼痛强度（使用VAS）、治疗前后的影像学变化、椎体骨折分级以及手术过程中椎体骨水泥向周围组织的体外渗漏情况。手术前后疼痛强度的差异具有统计学意义。所有患者术前均主诉疼痛（疼痛强度中位数为8），而术后所有患者的疼痛强度均下降（疼痛强度中位数为2）。总之，椎体成形术治疗骨髓瘤所致椎体骨折的临床效果改善显著。
