Aleris Obesity Clinic and Department of Surgery, Aleris Hospital, Oslo, Norway.
Obes Surg. 2020 Apr;30(4):1589-1595. doi: 10.1007/s11695-020-04420-8.
Reversal of Roux-en-Y gastric bypass (RYGB) to normal anatomy (NA) is mandated in selected cases. However, reversal operations are associated with high complication rates and long operative times. In this study, we present the functional reversal (FR) as a novel method and an alternative to reversal to NA in treating the otherwise intractable symptoms rarely occurring after RYGB.
This is a retrospective cohort study of RYGB-patients with symptoms resistant to non-surgical treatment. Placement of gastrostomy tube for surgical evaluation and optimization of patients was usually done before FR. Resolution of symptoms was assessed along with efficacy and safety of the procedure. Achieved results were compared with data from the literature pertaining to reversal to NA.
High-volume bariatric center, Norway.
Ten patients underwent FR. Mean follow-up after reversal was 18.4 months. Symptoms leading to operation improved in all patients. Eight patients suffered from hypoglycemia; resolution was seen in six and improvement of symptoms in the remaining two. Food intolerance, early dumping, nausea, postprandial abdominal pain, and malnutrition were alleviated in all patients. One leak was seen. Mean surgical time was 35.2 min. Total weight loss (TWL) and excess weight loss (EWL) after index RYGB were reduced 4.5% and 17.8%.
Functional reversal looks promising as an alternative to reversal to normal anatomy as it is technically simpler and safer and seems at least as effective in treating otherwise refractory symptoms.
在某些情况下,需要将 Roux-en-Y 胃旁路术(RYGB)逆转至正常解剖结构(NA)。然而,逆转手术与高并发症发生率和较长的手术时间相关。在这项研究中,我们提出了功能性逆转(FR)作为一种新的方法,用于治疗 RYGB 后罕见发生的、否则难以治疗的顽固性症状,而不是将其逆转至 NA。
这是一项对 RYGB 后出现症状且对非手术治疗有抗性的患者进行的回顾性队列研究。通常在 FR 之前通过放置胃造口管进行手术评估和患者优化。评估症状的缓解情况以及该手术的疗效和安全性。将所获得的结果与关于逆转至 NA 的文献数据进行比较。
高容量减重中心,挪威。
十名患者接受了 FR。逆转后平均随访时间为 18.4 个月。所有患者的症状均得到改善。八名患者患有低血糖症;六名患者症状得到缓解,两名患者症状得到改善。所有患者的食物不耐受、早期倾倒、恶心、餐后腹痛和营养不良均得到缓解。出现一例漏诊。手术时间平均为 35.2 分钟。RYGB 后的总体重减轻(TWL)和超重减轻(EWL)分别减少了 4.5%和 17.8%。
FR 作为逆转至正常解剖结构的替代方法具有广阔的前景,因为它在技术上更简单、更安全,并且在治疗其他顽固性症状方面似乎至少同样有效。