Neuroscience Graduate Program, University of California, Davis , Davis, CA, USA.
Department of Psychology, University of California, Davis , Davis, CA, USA.
J Psychoactive Drugs. 2020 Apr-Jun;52(2):113-122. doi: 10.1080/02791072.2020.1718250. Epub 2020 Jan 23.
Anecdotal reports suggest that the administration of sub-hallucinogenic doses of psychedelic compounds on a chronic, intermittent schedule - a practice known as psychedelic microdosing - is becoming increasingly popular among young adults due to its purported ability to reduce symptoms of depression and anxiety while improving cognitive function and promoting social interaction. Using an anonymous online survey, we collected data from 2347 people to 1) assess the prevalence of psychedelic microdosing and characterize the demographics of microdosers, 2) determine whether microdosers associate the practice with changes in mood, cognitive function, social interaction, or physiology, and 3) investigate frequent motives for discontinuing the practice. Fifty-nine percent of respondents (N= 2183) reported familiarity with the concept of psychedelic microdosing, with 17% (383 respondents, N = 2200) having engaged in this practice. Microdosers attributed psychedelic microdosing with improving their mood, decreasing their anxiety, and enhancing their memory, attention, and sociability. The most frequently cited reasons for quitting microdosing (N= 243) were the risks associated with taking an illegal substance (24.28%) and the difficulty of obtaining psychedelic compounds (22.63%). Overall, our findings suggest that psychedelic microdosing is relatively common and is subjectively associated with a broad spectrum of socio-affective, cognitive, and physical outcomes.
传闻表明,在慢性、间歇性的时间安排下,服用低致幻剂量的迷幻化合物——这种做法被称为迷幻微剂量——在年轻人中越来越流行,因为据称它可以减轻抑郁和焦虑症状,同时改善认知功能并促进社交互动。我们使用匿名在线调查收集了 2347 人的数据,以:1)评估迷幻微剂量的流行程度,并描述微剂量使用者的人口统计学特征;2)确定微剂量使用者是否将该做法与情绪、认知功能、社交互动或生理变化联系起来;3)调查停止该做法的常见动机。59%的受访者(N=2183)报告熟悉迷幻微剂量的概念,17%(N=2200,383 名受访者)曾从事过这种做法。微剂量使用者认为迷幻微剂量可以改善他们的情绪,减少他们的焦虑,并增强他们的记忆力、注意力和社交能力。(N=243)最常被引用的停止微剂量的原因是与服用非法物质相关的风险(24.28%)和获得迷幻化合物的难度(22.63%)。总的来说,我们的研究结果表明,迷幻微剂量相对常见,并且在主观上与广泛的社会情感、认知和身体结果相关。