South London and Maudsley NHS Trust/King's College London, London, UK.
School of Public Health, The University of Queensland, Brisbane, QLD, Australia.
J Psychopharmacol. 2024 Aug;38(8):735-748. doi: 10.1177/02698811241254837. Epub 2024 May 28.
The recreational use of LSD, a synthetic psychedelic drug, has surged in recent years, coinciding with a renewed research focus on its potential psychotherapeutic properties.
This study aims to describe the experiences and perceptions of individuals engaging in LSD use for the first time, derived from a large international sample.
This study utilised 2018 Global Drug Survey data collected from 6 November 2017 to 10 January 2018. Participants who initiated LSD use in the preceding 12 months answered questions on their experiences, social settings, harm-reduction behaviours, and demographics. Descriptive statistics were employed, and characteristics of those seeking emergency medical treatment (EMT) and those not planning further LSD use were compared with other respondents.
Among 3340 respondents who used LSD in the past year, their first-time experiences generally exceeded expectations, with 97.7% expressing excitement. Adverse and unwanted side effects were rarely reported, and only 17 individuals needed EMT. Feelings of fear were reported by most (64.1%), but only very mildly and not enough to put them off from wanting to use LSD again.
Although the occurrence of unwanted side effects seems low and the LSD experience is generally pleasurable, vigilance amid the rising illicit use of LSD through harm-reduction education is still important in preventing possible risks.
近年来,迷幻药 LSD(一种合成迷幻药物)的娱乐性使用呈上升趋势,恰逢人们对其潜在心理治疗特性的研究重新关注。
本研究旨在描述首次使用 LSD 的个体的体验和看法,这些个体来自一个大型国际样本。
本研究利用了 2018 年全球毒品调查数据,这些数据是在 2017 年 11 月 6 日至 2018 年 1 月 10 日期间收集的。在过去 12 个月内首次使用 LSD 的参与者回答了关于他们的体验、社交环境、减少伤害行为和人口统计学的问题。采用描述性统计方法,比较了寻求紧急医疗救治(EMT)和不打算进一步使用 LSD 的人的特征与其他受访者。
在过去一年中使用 LSD 的 3340 名受访者中,他们的首次体验普遍超出预期,97.7%的人表示兴奋。很少有不良和不愉快的副作用报告,只有 17 人需要 EMT。大多数人(64.1%)报告感到恐惧,但只是非常轻微,不足以阻止他们再次使用 LSD。
尽管不良副作用的发生似乎较低,而且 LSD 体验通常令人愉悦,但在通过减少伤害教育警惕 LSD 非法使用不断增加的情况下,仍重要的是要预防可能的风险。