The Department of Cellular and Integrative Physiology, Fukushima Medical University, Fukushima, Japan.
The Department of Ophthalmology, Fukushima Medical University, Fukushima, Japan.
Sci Rep. 2020 Jan 23;10(1):1088. doi: 10.1038/s41598-020-57788-z.
The choroid is a complex vascular tissue that is covered with the retinal pigment epithelium. Ultra high speed swept source optical coherence tomography (SS-OCT) provides us with high-resolution cube scan images of the choroid. Robust segmentation techniques are required to reconstruct choroidal volume using SS-OCT images. For automated segmentation, the delineation of the choroidal-scleral (C-S) boundary is key to accurate segmentation. Low contrast of the boundary, scleral canals formed by the vessel and the nerve, and the posterior stromal layer, may cause segmentation errors. Semantic segmentation is one of the applications of deep learning used to classify the parts of images related to the meanings of the subjects. We applied semantic segmentation to choroidal segmentation and measured the volume of the choroid. The measurement results were validated through comparison with those of other segmentation methods. As a result, semantic segmentation was able to segment the C-S boundary and choroidal volume adequately.
脉络膜是一种覆盖视网膜色素上皮的复杂血管组织。超高速扫频源光相干断层扫描(SS-OCT)为我们提供了脉络膜的高分辨率立方扫描图像。使用 SS-OCT 图像重建脉络膜体积需要强大的分割技术。对于自动分割,脉络膜-巩膜(C-S)边界的描绘是准确分割的关键。边界对比度低、血管和神经形成的巩膜管以及后基质层可能导致分割错误。语义分割是深度学习的应用之一,用于对与主题含义相关的图像部分进行分类。我们将语义分割应用于脉络膜分割并测量了脉络膜的体积。通过与其他分割方法的比较验证了测量结果。结果表明,语义分割能够充分分割 C-S 边界和脉络膜体积。