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成人哮喘穴位埋线疗法:系统评价方案

Acupoint catgut embedding for asthma in adults: Protocol for a systematic review.

作者信息

Lu Xiaoxiao, Wu Xianming, Wu Xingrong, Chen Panbi, Cui Jin

机构信息

Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu.

Guizhou University of Traditional Chinese Medicine, Guiyang, China.

出版信息

Medicine (Baltimore). 2020 Jan;99(4):e18933. doi: 10.1097/MD.0000000000018933.

Abstract

BACKGROUND

Asthma exacerbations can do a lot of harm to the patients and consume large amounts of medical resources. Although some studies have evaluated acupuncture for asthma in children, few studies have estimated acupoint catgut embedding therapy. We aim to assess the efficacy and safety of acupoint catgut embedding for asthma in adults.

METHODS

The following databases will be searched from inception to December, 2019: Medline, Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, EMBASE, the China National Knowledge Infrastructure Database (CNKI), the Chinese Scientific Journal Database (VIP database), and the Wan-fang database. We will also search relevant conference abstracts, and registers of clinical trials. Two reviewers will independently undertake study selection, data extraction, and quality assessment. Data will be synthesized by either the fixed-effects or random-effects model according to a heterogeneity test. The Revman V5.3 software will be used to conduct meta-analysis.

RESULTS

The primary outcome was lung function, forced expiratory volume in one second and forced vital capacity (FVC) were the most commonly used parameters to evaluate lung function. The safety assessment includes the incidence of adverse events.

CONCLUSION

This systematic review will retrieve clinical randomized controlled trials (RCT) on acupoint catgut embedding for asthma in 7 databases, aiming to describe and update existing evidence on the efficacy and safety of acupoint catgut embedding for asthma in adults.PROSPERO registration number: CRD42019148401.

摘要

背景

哮喘急性发作会对患者造成诸多危害,并消耗大量医疗资源。尽管一些研究评估了针刺疗法对儿童哮喘的疗效,但评估穴位埋线疗法的研究较少。我们旨在评估穴位埋线治疗成人哮喘的疗效和安全性。

方法

将检索以下数据库,检索时间从建库至2019年12月:医学索引数据库(Medline)、考克兰系统评价数据库(CENTRAL)、美国国立医学图书馆生物医学数据库(PubMed)、荷兰医学文摘数据库(EMBASE)、中国知网数据库(CNKI)、维普中文科技期刊数据库(VIP数据库)和万方数据库。我们还将检索相关会议摘要和临床试验注册库。两名研究者将独立进行研究筛选、数据提取和质量评估。根据异质性检验,采用固定效应模型或随机效应模型对数据进行合并。将使用Revman V5.3软件进行荟萃分析。

结果

主要结局指标为肺功能,一秒用力呼气容积和用力肺活量(FVC)是评估肺功能最常用的参数。安全性评估包括不良事件的发生率。

结论

本系统评价将检索7个数据库中关于穴位埋线治疗哮喘的临床随机对照试验(RCT),旨在描述和更新现有关于穴位埋线治疗成人哮喘疗效和安全性的证据。国际前瞻性注册系统(PROSPERO)注册号:CRD42019148401。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b21/7004599/546ccf398ca0/medi-99-e18933-g002.jpg

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