Suppr超能文献

采用混合纳米复合材料和增材CAD/CAM技术制作全口义齿的以患者为中心的结果评估的18个月随访

Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol.

作者信息

Cristache Corina Marilena, Totu Eugenia Eftimie, Iorgulescu Gabriela, Pantazi Aida, Dorobantu Dorel, Nechifor Aurelia Cristina, Isildak Ibrahim, Burlibasa Mihai, Nechifor Gheorghe, Enachescu Marius

机构信息

Department of Dental Techniques, Faculty of Midwifery and Medical Assisting (FMAM), "Carol Davila" University of Medicine and Pharmacy, 8, Eroilor Sanitari Blvd, 050474 Bucharest, Romania.

Department of Analytical Chemistry, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu St., sector 1, 011061 Bucharest, Romania.

出版信息

J Clin Med. 2020 Jan 23;9(2):324. doi: 10.3390/jcm9020324.

Abstract

UNLABELLED

The present study aimed to assess the eighteen month follow-up patient-centered outcomes of a simple and predictable protocol for 3D-printed functional complete dentures manufactured using an improved poly(methyl methacrylate) (PMMA)-nanoTiO. A detailed morphological and structural characterization of the PMMA-TiO nanocomposite, using SEM, EDX, XRD, and AFM, after 3D-printing procedure and post-wearing micro-CT, was also performed.

METHODS

A total of 35 fully edentulous patients were enrolled in this prospective study. A 0.4% TiO-nanoparticle-reinforced PMMA composite with improved mechanical strength, morphologically and structurally characterized, was used according to an additive computer-aided design and computer-aided manufacturing (CAD/CAM) protocol for complete denture fabrication. The protocol proposed involved a three-step appointment process. Before denture insertion, 1 week, 12 month, and 18-month follow up patients were evaluated via the Visual Analogue Scale (VAS, 0-10) and Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT), with a higher score meaning poor quality of life.

RESULTS

A total of 45 complete denture sets were inserted. OHIP-EDENT scored significantly better after 18 months of denture wearing, 20.43 (±4.42) compared to 52.57 (±8.16) before treatment; mean VAS was improved for all parameters assessed.

CONCLUSIONS

Within the limitations of this study, we can state that the proposed workflow with the improved material used is a viable treatment option for patients diagnosed with complete edentulism.

摘要

未标注

本研究旨在评估采用改进的聚甲基丙烯酸甲酯(PMMA)-纳米TiO₂ 3D打印功能性全口义齿的简单且可预测方案的18个月随访以患者为中心的结果。还对3D打印过程后及佩戴后微CT扫描的PMMA-TiO₂纳米复合材料进行了详细的形态学和结构表征,采用扫描电子显微镜(SEM)、能谱仪(EDX)、X射线衍射仪(XRD)和原子力显微镜(AFM)。

方法

本前瞻性研究共纳入35例全口无牙患者。根据用于全口义齿制作的增材计算机辅助设计和计算机辅助制造(CAD/CAM)方案,使用一种机械强度得到改善、经形态学和结构表征的含0.4% TiO₂纳米颗粒增强的PMMA复合材料。所提出的方案包括三步预约流程。在义齿佩戴前、佩戴1周、12个月和18个月随访时,通过视觉模拟评分法(VAS,0-10)和无牙患者口腔健康影响量表(OHIP-EDENT)对患者进行评估,分数越高表明生活质量越差。

结果

共佩戴了45副全口义齿。佩戴义齿18个月后,OHIP-EDENT评分显著改善,为20.43(±4.42),而治疗前为52.57(±8.16);所有评估参数的平均VAS均有所改善。

结论

在本研究的局限性范围内,我们可以说,所提出的使用改进材料的工作流程对于被诊断为全口无牙症的患者是一种可行的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/566f/7073708/efc1f0c84b51/jcm-09-00324-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验