从双壳贝类中分离到的真菌 sp. SCS-KFD66 中得到 Asperpenes D 和 E。
Asperpenes D and E from the fungus sp. SCS-KFD66 isolated from a bivalve mollusk, .
机构信息
Haina Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
出版信息
J Asian Nat Prod Res. 2021 Feb;23(2):117-122. doi: 10.1080/10286020.2019.1709450. Epub 2020 Jan 24.
Two new compounds named asperpenes D () and E () were isolated from the marine-derived fungus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2,5-dihydrofuran-3-carboxylic acid skeleton. All the compounds were tested for enzyme inhibitory activity against AChE and α-glucosidase and DPPH radical scavenging activity, respectively. [Formula: see text].
从海洋来源的真菌 Aspergillus sp. SCS-KFD66 中分离得到两个新化合物 Asperpenes D () 和 E ()。根据光谱方法确定了它们的结构。化合物 代表了第一个含有 2-取代-5-氧代-4-苯基-2,5-二氢呋喃-3-羧酸骨架的天然产物。所有化合物均进行了乙酰胆碱酯酶和 α-葡萄糖苷酶抑制活性以及 DPPH 自由基清除活性测试。[化学式：见正文]。
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