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巴西含麻疹疫苗:覆盖范围、覆盖率的同质性以及与市级背景因素的关联。

Measles-containing vaccines in Brazil: Coverage, homogeneity of coverage and associations with contextual factors at municipal level.

机构信息

Post-Graduation Program in Health Sciences, University of Brasília, Brasília, DF, Brazil; Secretariat of Health Surveillance, Ministry of Health, Brasília, DF, Brazil.

Post-Graduation Program in Health Sciences, University of Brasília, Brasília, DF, Brazil; Secretariat of Health Surveillance, Ministry of Health, Brasília, DF, Brazil.

出版信息

Vaccine. 2020 Feb 18;38(8):1881-1887. doi: 10.1016/j.vaccine.2020.01.030. Epub 2020 Jan 22.

DOI:10.1016/j.vaccine.2020.01.030
PMID:31980195
Abstract

We aimed to (i) describe both the coverage and the homogeneity of coverage of the first and second doses of measles-containing vaccines (MCV) in Brazil in 2017, and (ii) to investigate the potential influence of contextual factors at municipal level. All 5570 Brazilian municipalities were included. The North and Center-West regions presented the lowest coverages of the first and second doses of MCV, respectively. We found significant associations of both first and second doses of MCV with population size, coverage of Family Health Strategy (FHS) and other indicators of living conditions and inequalities. Monitoring the homogeneity of MCV coverage at national, regional and state levels is essential, as it allows identifying areas at higher risk of measles spread that should be targeted for vaccination. Targeting large cities i.e. 100,000 or more inhabitants, especially poor neighborhoods and areas with low FHS coverage, could lead to improvements in coverage homogeneity.

摘要

我们的目的是

(i)描述 2017 年巴西第一剂和第二剂含麻疹疫苗(MCV)的覆盖范围和覆盖均匀性;(ii)研究市级背景因素的潜在影响。纳入了巴西所有 5570 个城市。北部和中西部地区的 MCV 第一剂和第二剂覆盖率最低。我们发现 MCV 第一剂和第二剂的接种覆盖率与人口规模、家庭健康战略(FHS)覆盖率以及其他生活条件和不平等指标均显著相关。监测全国、地区和州各级 MCV 覆盖的均匀性至关重要,因为这可以识别麻疹传播风险较高的地区,以便为这些地区的接种提供目标。以大城市(即 10 万或以上居民)为目标,特别是贫困社区和 FHS 覆盖率较低的地区,可能会提高覆盖率的均匀性。

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