National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India.
Department of Biological Sciences, Aliah University, IIA/27-Newtown, Kolkata 700160, India.
Life Sci. 2020 Mar 15;245:117350. doi: 10.1016/j.lfs.2020.117350. Epub 2020 Jan 23.
Resveratrol is an important phenolic phytochemical from the therapeutic perspective. It has therapeutic impacts over wide range of diseases, especially the ones related to oxidative stress. Resveratrol, being primarily a potent anti-oxidant phytochemical, has significant impact against major diseases as inflammatory disorders, diabetes, and cancer. In the current review article, we intend to highlight the molecular aspects of the mechanism of action of resveratrol against major diabetic implications, namely, retinopathy and neuropathy. Both these diabetic implications are among the first fallouts of chronic hyperglycaemia. Resveratrol, via multiple molecular pathways, tend to attenuate and reverse these deformity and other disease-causing implications.
白藜芦醇是一种重要的酚类植物化学物质，具有广泛的治疗作用，特别是对与氧化应激相关的疾病。白藜芦醇主要是一种有效的抗氧化植物化学物质，对炎症性疾病、糖尿病和癌症等主要疾病有显著影响。在这篇综述文章中，我们旨在强调白藜芦醇对主要糖尿病并发症（即视网膜病变和神经病变）的作用机制的分子方面。这两种糖尿病并发症都是慢性高血糖的早期后果之一。白藜芦醇通过多种分子途径，减轻和逆转这些畸形和其他致病影响。
