Vargas Adriana Cunha, Dell Agnolo Catia, Melo Willian Augusto de, Pelloso Fernando Castilho, Santos Lander Dos, Carvalho Maria Dalva de Barros, Pelloso Sandra Marisa
Department of Health Sciences, Maringá State University, Maringa, Paraná, Brazil.
Department of Nursing, Paraná State University, UNESPAR Av. Gabriel Esperidião, S / N - Jd. Morumbi, Paranavaí, Brazil.
Asian Pac J Cancer Prev. 2020 Jan 1;21(1):55-62. doi: 10.31557/APJCP.2020.21.1.55.
This study aimed to analyze the trend in cervical cancer (ICD C53) mortality in Brazilian regions in women who are who are screened and not screened from 1996 to 2015.
An epidemiological study, of time series of mortality from cervical cancer performed in 90,856 women under 24 years old (343 women), between 25 and 64 years old (32,703 women), and over 65 years old (10,909 women). The data from this research were collected from the DATASUS, from the SIM Health Surveillance Secretariat files, captured through TABNET selecting the resident population by gender and age group and ICD 10 C53 from 1996 to 2015.
Among women, 43.8% were white, and 76% had less than eight years of formal education. Polynomial regression showed an increasing trend in cervical cancer mortality in Brazil for women aged 15 - 24 years (p=0.01). Between 25 - 64 and 65 years or older it remained constant, but high (p=0.07; 0.99). The Northeast region pointed a growing trend in women aged 15 to 24 (p=0.01), 25 to 64 years (p=0.01) and 65 or older (p=0.001). The Northeast presented the highest average growth per year. In the Southeast, South and Midwest regions, decreasing trends were observed despite the high rates. The Joinpoint regression showed a 95% confidence interval, and that mortality from cervical cancer in the North region increased throughout the period analyzed. an increasing trend was observed from 1996 to 1998, whereas in the Midwest region, the trend remained stable throughout the period analyzed. The Federal District presented an upward trend from 1996 to 2015. In Brazil, an upward trend was observed throughout the whole period analyzed.
Cervical cancer mortality in younger women is becoming more predominant, in addition to the high rate observed for women aged 65 or older.
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本研究旨在分析1996年至2015年巴西各地区筛查和未筛查女性宫颈癌(ICD C53)死亡率的趋势。
对90856名女性进行宫颈癌死亡率时间序列的流行病学研究,这些女性年龄在24岁以下(343名女性)、25至64岁(32703名女性)以及65岁以上(10909名女性)。本研究数据收集自DATASUS,来自SIM健康监测秘书处文件,通过TABNET按性别和年龄组以及1996年至2015年的ICD 10 C53选择常住人口。
在女性中,43.8%为白人,76%接受的正规教育年限少于8年。多项式回归显示,巴西15至24岁女性的宫颈癌死亡率呈上升趋势(p = 0.01)。在25至64岁以及65岁及以上年龄段,死亡率保持稳定,但仍处于高位(p = 0.07;0.99)。东北地区15至24岁(p = 0.01)、25至64岁(p = 0.01)以及65岁及以上(p = 0.001)女性呈现上升趋势。东北地区每年的平均增长率最高。在东南部、南部和中西部地区,尽管死亡率较高,但仍呈下降趋势。Joinpoint回归显示95%置信区间,且北部地区宫颈癌死亡率在整个分析期内呈上升趋势。1996年至1998年观察到上升趋势,而在中西部地区,整个分析期内趋势保持稳定。联邦区在1996年至2015年呈上升趋势。在巴西,整个分析期内均观察到上升趋势。
除65岁及以上女性的高死亡率外,年轻女性的宫颈癌死亡率正变得更加突出。