Bruyère Research Institute, Ottawa, Ontario, Canada.
School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.
J Clin Exp Neuropsychol. 2020 May;42(4):344-351. doi: 10.1080/13803395.2020.1714552. Epub 2020 Jan 26.
: We examined the extent to which loss of consciousness (LOC) following mild traumatic brain injury (mTBI) may be associated with impairments in executive functions and declarative memory more than a year after brain injury.: Analyses were run on 548 participants who had self-reported LOC of <1 min, 441 with LOC of 1-20 min, and 13,609 no brain injury comparison participants, taken from the Canadian Longitudinal Study on Aging (CLSA), a nationwide study on health and aging.: Those that had mTBI with LOC of 1-20 min were more likely than no head injury comparisons to be impaired on measures of executive functioning and declarative memory. Impairments were evident when examining for single- and two-test impairment rates on measures of executive functioning and declarative memory.: A subset of people that had reported a single mTBI with LOC more than 12 months ago may experience impairments in executive functioning and declarative memory, particularly those who spent more time unconscious.
我们研究了轻度创伤性脑损伤(mTBI)后意识丧失(LOC)与执行功能和陈述性记忆受损之间的关系,这种受损在脑损伤一年后仍然存在。
对来自加拿大老龄化纵向研究(CLSA)的 548 名自述 LOC <1 分钟、441 名 LOC 为 1-20 分钟、13609 名无脑损伤对照组参与者进行了分析,这是一项关于健康和老龄化的全国性研究。
与无脑损伤对照组相比,那些有 1-20 分钟 LOC 的 mTBI 更有可能在执行功能和陈述性记忆测试中受损。在检查执行功能和陈述性记忆测试的单测和双测受损率时,发现了这些损伤。
一组报告过去 12 个月以上有单次 mTBI 且 LOC 超过 12 分钟的人可能会出现执行功能和陈述性记忆受损,尤其是那些无意识时间较长的人。