新型抗真菌抗生素二十八元大环内酯A和B。II. 运用多种核磁共振光谱方法进行结构解析。
Novel antifungal antibiotics octacosamicins A and B. II. The structure elucidation using various NMR spectroscopic methods.
作者信息
Dobashi K, Naganawa H, Takahashi Y, Takita T, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1988 Nov;41(11):1533-41. doi: 10.7164/antibiotics.41.1533.
PMID:3198489
Abstract
The structures of octacosamicins A and B, two new antifungal antibiotics, were studied by spectrometries and chemical modifications. The 2D NMR techniques including 1H-detected heteronuclear multiple bond correlation method were successfully applied to this study. These antibiotics have unique linear chain structure possessing N-hydroxyguanidyl group at the terminal.
摘要
通过光谱学和化学修饰研究了两种新型抗真菌抗生素八肽霉素A和B的结构。包括1H检测异核多键相关方法在内的二维核磁共振技术成功应用于该研究。这些抗生素具有独特的线性链结构，末端带有N-羟基胍基。
Zotero 插件