Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India.
Curr Protein Pept Sci. 2020;21(6):584-597. doi: 10.2174/1389203721666200127112244.
The peptides containing β-and γ-amino acids as building blocks display well-defined secondary structures with unique morphologies. The ability of such peptides to self-assemble into complex structures of controlled geometries has been exploited in biomedical applications. Herein, we have provided an updated overview about the peptides containing β-and γ-amino acids considering the significance and advancement in the area of development of peptide-based biomaterials having diverse applications.
含β-和γ-氨基酸作为构建块的肽显示出具有独特形态的明确的二级结构。这些肽能够自组装成具有受控几何形状的复杂结构,这一特性已在生物医学应用中得到了利用。本文综述了含β-和γ-氨基酸的肽,考虑了在具有多种应用的基于肽的生物材料的开发领域中的重要性和进展。